A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery

• Published in: Journal of global infectious diseases Vol. 15; no. 2; pp. 81 - 83
• Main Authors: Ostapchuk, Yekaterina O, Dmitrovskiy, Andrey M, Pak, Elena A, Perfilyeva, Yuliya V
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.04.2023; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Antibiotics; Antiviral drugs; borrelia burgdorferi s. l; Case Report; Case studies; Development and progression; Diuretics; Encephalitis; Fever; Health aspects; Immunoglobulin G; Infection; kazakhstan; lyme neuroborreliosis; Meningitis; Meningoencephalitis; Nausea; Parasitic diseases; Rural areas; Sweating; Tick-borne encephalitis; tick-borne encephalitis virus; Vomiting; Kazakhstan; tick-borne encephalitis; meningoencephalitis; Borrelia burgdorferi s. l; Kazakhstan; lyme neuroborreliosis; tick-borne encephalitis virus
• ISSN: 0974-777X; 0974-8245
• DOI: 10.4103/jgid.jgid_76_22

Here, we present a case of severe meningoencephalitis caused by combined infection with tick-borne encephalitis (TBE) and Lyme borreliosis (LB) in a 25-year-old woman in a rural area of Zhambyl region, Kazakhstan. She presented with fever, nausea, vomiting, weakness, sweating, severe headache, arthralgia, and malaise. The course of illness was further complicated by encephalitis with symmetric lesions of the midbrain cerebral peduncles and serous meningitis. TBE and LB co-infection were established by a two-fold increase in serum IgG titers between day 21 and day 25 of illness. Both infections responded well to combined therapy with human TBE immunoglobulins, antibiotics, antiviral drugs, glucocorticoids, and diuretics. The outcome of the disease was favorable and the patient recovered completely.