Genetics and Genomics of Social Behavior in a Chicken Model

The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identif...

Full description

Saved in:
Bibliographic Details
Published inGenetics (Austin) Vol. 209; no. 1; pp. 209 - 221
Main Authors Johnsson, Martin, Henriksen, Rie, Fogelholm, Jesper, Höglund, Andrey, Jensen, Per, Wright, Dominic
Format Journal Article
LanguageEnglish
Published United States Genetics Society of America 01.05.2018
Subjects
Animal behavior
Animals
Anxiety
Behavior, Animal
Birds
Chickens
Chickens - genetics
Gallus gallus
Genes
Genetics
Genetik
Genomics
Genomics - methods
Genotype
Hypothalamus
Investigations
Kinases
Phenotype
Poultry
Quantitative Trait Loci
Quantitative Trait, Heritable
Reinstatement
Social Behavior
Zebrafish
QTL
eQTL
behavior
sociality
Online AccessGet full text

Cover

More Information
Summary:The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identify genes for social reinstatement, a social and anxiety-related behavior. A total of 24 social reinstatement QTL were identified and overlaid with over 600 eQTL obtained from the same birds using hypothalamic tissue. Correlations between overlapping QTL and eQTL indicated five strong candidate genes, with the gene being strongly significantly correlated with multiple aspects of social reinstatement behavior, as well as possessing a highly significant eQTL.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1943-2631
0016-6731
1943-2631
DOI:10.1534/genetics.118.300810