Sensory disturbance and polyneuropathy in rheumatoid arthritis patients with foot deformity

Our aim in this study was to present the results of sensory evaluation tests and electrophysiological evaluations in rheumatoid arthritis (RA) patients with foot deformity and to determine their relation with general health status and lower extremity functionality. Fifty-one patients with RA diagnos...

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Published inRevista Brasileira de Reumatologia Vol. 56; no. 3; pp. 191 - 197
Main Authors Karaca Umay, Ebru, Gurcay, Eda, Karsli, Pinar Bora, Cakci, Aytul
Format Journal Article
LanguageEnglish
Published Brazil Elsevier Editora Ltda 01.05.2016
Sociedade Brasileira de Reumatologia
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Summary:Our aim in this study was to present the results of sensory evaluation tests and electrophysiological evaluations in rheumatoid arthritis (RA) patients with foot deformity and to determine their relation with general health status and lower extremity functionality. Fifty-one patients with RA diagnosis and foot deformity were included in the study. Demographic and disease characteristics of the patients were recorded, and a detailed neurological examination was performed. Superficial sensation, pain, heat, vibration, and two-point discrimination sensation were evaluated in each foot, and their sum was used to determine the sensory deficits index (SDI) of 0–10. The presence of polyneuropathy was evaluated with electrophysiological methods. The Health Assessment Questionnaire and mobility and walking subscales of the Arthritis Impact Measurement Scales-2 were used to assess general health status and lower extremity functionality, respectively. According to the sensory examination and electromyography results, patients were compared in terms of their general health status and lower extremity functional status. Sensory disturbance was detected in 39 patients (74%) during the examination; however, 27 patients (52.9%) had polyneuropathy determined electrophysiologically. In patients with sensory deficits, statistically significant deterioration was detected in general health and foot functionality, including mobility and walking, when compared to patients with a normal sensory evaluation. Even in the presence of normal electrophysiological tests, sensory dysfunction alone seems to be associated with severe disability in general health status and foot functionality when compared to patients with a normal sensory examination. O objetivo deste estudo foi apresentar os resultados dos testes de avaliação sensitiva e exame eletrofisiológico em pacientes com artrite reumatoide (AR) com deformidade do pé e determinar a sua relação com o estado geral de saúde e aspecto funcional dos membros inferiores. Foram incluídos no estudo 51 pacientes com diagnóstico de AR e deformidade do pé. Foram registradas as características demográficas e da doença de cada indivíduo, e foi realizado um exame neurológico detalhado. Foi avaliada a sensibilidade superficial, sensibilidade dolorosa, sensibilidade térmica, sensibilidade vibratória e aplicado o teste de discriminação de dois pontos em cada um dos pés, e a soma dos escores foi usada para determinar o índice de déficits sensitivos (IDS) de 0-10. A presença de polineuropatia foi avaliada com métodos eletrofisiológicos. Foi utilizado o Health Assessment Questionnaire e as subescalas mobilidade e deambulação da Arthritis Impact Measurement Scales-2 para avaliar o estado geral de saúde e o aspecto funcional de membros inferiores, respectivamente. De acordo com os resultados dos exames de eletromiografia e de sensibilidade, os pacientes foram comparados em relação ao seu estado geral de saúde e estado funcional de membros inferiores. Foram detectados distúrbios sensitivos em 39 pacientes (74%) durante o exame; contudo, 27 deles (52,9%) tinham polineuropatia determinada eletrofisiologicamente. Em pacientes com déficits sensitivos, foi detectada deterioração estatisticamente significativa no estado geral de saúde e no aspecto funcional do pé, inclusive na mobilidade e deambulação, quando comparados aos pacientes com uma avaliação sensitiva normal. Mesmo na presença de testes eletrofisiológicos normais, a disfunção sensitiva isolada parece estar associada a incapacidade grave no estado geral de saúde e no aspecto funcional do pé em comparação a pacientes com um exame sensitivo normal.
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ISSN:2255-5021
1809-4570
2255-5021
DOI:10.1016/j.rbre.2015.08.010