Mechanisms Underlying Memory Consolidation by Adult-Born Neurons During Sleep

• Published in: Frontiers in cellular neuroscience Vol. 14; p. 594401
• Main Authors: Vergara, Pablo, Sakaguchi, Masanori
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 26.11.2020
• Subjects: adult-neurogenesis; Cellular Neuroscience; hippocampus; memory consolidation; REM sleep; synaptic plasticity; theta oscillation; theta oscillation; hippocampus; memory consolidation; optogenetics; adult-neurogenesis; synaptic plasticity; calcium-imaging; REM sleep

The mammalian hippocampus generates new neurons that incorporate into existing neuronal networks throughout the lifespan, which bestows a unique form of cellular plasticity to the memory system. Recently, we found that hippocampal adult-born neurons (ABNs) that were active during learning reactivate...