Insecticide and acaricide molecules and/or combinations to prevent pet infestation by ectoparasites

• Published in: Trends in parasitology Vol. 28; no. 7; pp. 267 - 279
• Main Authors: Beugnet, Frédéric, Franc, Michel
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.07.2012; Elsevier
• Subjects: acaricide; acaricides; Acaricides - adverse effects; Acaricides - chemistry; Acaricides - pharmacology; active ingredients; Animals; antiparasitic agents; Arthropods - drug effects; Biological and medical sciences; Cat Diseases - drug therapy; Cat Diseases - parasitology; Cat Diseases - transmission; Cats; Dog Diseases - drug therapy; Dog Diseases - parasitology; Dog Diseases - transmission; Dogs; Drug Therapy, Combination; drugs; ectoparasites; Ectoparasitic Infestations - drug therapy; Ectoparasitic Infestations - prevention & control; Ectoparasitic Infestations - transmission; Ectoparasitic Infestations - veterinary; Gastroenterology and Hepatology; General aspects; Infectious Disease; Infectious diseases; innovation; insecticide; Insecticides - adverse effects; Insecticides - chemistry; Insecticides - pharmacology; insects; long acting; markets; Medical sciences; mites; neonicotinoid insecticides; Organophosphates - adverse effects; Organophosphates - chemistry; Organophosphates - pharmacology; Parasitic diseases; Parasitic Diseases, Animal - drug therapy; Parasitic Diseases, Animal - prevention & control; Parasitic Diseases, Animal - transmission; parasitology; Permethrin - adverse effects; Permethrin - chemistry; Permethrin - pharmacology; spectrum; acaricide; innovation; insecticide; spectrum; long acting; Molecules; Acaricide; Insecticide; Pesticides; Parasite; Ectoparasite; Infestation
• ISSN: 1471-4922; 1471-5007; 1471-5007
• DOI: 10.1016/j.pt.2012.04.004

External antiparasitic drugs used in cats and dogs have evolved in terms of active ingredients but also regarding formulations. Old chemical groups have been supplanted by phenylpyrazoles, neonicotinoids, oxadiazines, spinosyns or others which are entering the veterinary market. In addition to insecticides–acaricides, insect and mite growth inhibitors (IGRs) have emerged. These IGRs are used in animals or in the environment, either alone or in combination with insecticides–acaricides. The notion of antiparasitic treatment has evolved to the concept of prevention of ectoparasite infestation but also of transmitted diseases through the introduction of formulations providing long-lasting activity. At the same time, ease-of-use has been improved with the development of spot-on formulations. Progress has also been achieved through the development of antiparasitic drugs providing control of both external and internal parasites.