Total Knee Arthroplasty for Osteoarthritis in a Patient with Nail Patella Syndrome - A Case Report

Hereditary osteo-onychodysplasia (or nail patella syndrome) is a rare autosomal dominant disease defined by an association of severe characteristics, with a classic clinical tetrad of dysplasia of the fingernails, patellar hypoplasia or absence, presence of iliac horns, and deformities of the elbow,...

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Bibliographic Details
Published inInternational medical case reports journal Vol. 14; pp. 871 - 876
Main Authors Serrano, Antonio Filipe, Serrano, Pedro Manuel
Format Journal Article
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2021
Taylor & Francis Ltd
Dove
Dove Medical Press
Subjects
adult
Arthritis
Care and treatment
Case Report
Case reports
Dysplasia
Genetic aspects
hereditary onycho- osteodysplasia
Joint replacement surgery
Joint surgery
Knee
Orthopedics
Osteoarthritis
Pain
patellar aplasia
Patients
Physical therapy
Quality of life
total knee arthroplasty
X-rays
Portugal
hereditary onycho-osteodysplasia
total knee arthroplasty
patellar aplasia
adult
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Summary:Hereditary osteo-onychodysplasia (or nail patella syndrome) is a rare autosomal dominant disease defined by an association of severe characteristics, with a classic clinical tetrad of dysplasia of the fingernails, patellar hypoplasia or absence, presence of iliac horns, and deformities of the elbow, although renal, ocular and neurological involvement may also be present. The main orthopedic complaint of these patients is patellar instability associated with pain and functional limitation. Most of the literature regarding the treatment of NPS-related patellar problems, concerns pediatric population and there is no treatment algorithm defined for adult patients. NPS has a wide range of presentations in skeletally mature patients, and its severity is also very variable. The general practitioner should be familiar with NPS's clinical presentation spectrum, and the orthopedic surgeon with treatment options, in order to provide the most adequate treatment for each patient. Although there is no cure for NPS, several treatments have been useful in the symptomatic treatment of changes in the knees. We describe a rare clinical case of a 47-year-old female patient with NPS who underwent total knee arthroplasty for knee osteoarthritis.
ISSN:1179-142X
1179-142X
DOI:10.2147/IMCRJ.S345262