Efficacy and safety of ovarian stimulation before chemotherapy in 205 cases

• Published in: Fertility and sterility Vol. 94; no. 7; pp. 2871 - 2873
• Main Authors: Lawrenz, Barbara, M.D, Jauckus, Julia, Kupka, Markus, M.D, Strowitzki, Thomas, M.D, von Wolff, Michael, M.D
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.12.2010; Elsevier
• Subjects: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols - administration & dosage; Antineoplastic Combined Chemotherapy Protocols - adverse effects; Biological and medical sciences; Cancer; cryopreservation; Cryopreservation - methods; Drug Administration Schedule; Female; fertility preservation; Follow-Up Studies; Gynecology. Andrology. Obstetrics; Humans; Infertility, Female - etiology; Infertility, Female - prevention & control; Internal Medicine; IVF; Medical sciences; Neoplasms - complications; Neoplasms - drug therapy; Obstetrics and Gynecology; Oocytes; Ovulation Induction - adverse effects; Ovulation Induction - methods; Pregnancy; Pregnancy Rate; Registries; Time Factors; Treatment Outcome; Young Adult; IVF; fertility preservation; oocytes; cryopreservation; Cancer; Ovarian stimulation; Preservation; Gynecology; Malignant tumor; Obstetrics; In vitro fertilization embryo transfer; Chemotherapy; Treatment; Cryopreservation; Fertility; Safety; Oocyte
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/j.fertnstert.2010.06.054

Ovarian stimulation and cryopreservation of fertilized oocytes before cancer therapy is the best established and efficient fertility preservation technique and should still be considered before chemotherapy. Within a short time frame of 2 weeks, between 8.6 (18–25 y) and 5.1 (36–40 y) fertilized oocytes can be cryopreserved.