SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23

• Published in: BMC cancer Vol. 24; no. 1; pp. 210 - 10
• Main Authors: Wu, Yongkang, Chen, Weijie, Miao, Huilai, Xu, Tuo
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.02.2024; BioMed Central; BMC
• Subjects: Analysis; Anaplastic thyroid cancer; Antibodies; Biotechnology; Cancer therapies; Care and treatment; Cell migration; Cell proliferation; Cell viability; Cells; Diagnosis; Gene expression; Genetic aspects; Health aspects; Immunoprecipitation; KIF23; Kinesin; Medical prognosis; Migration; Penicillin; Proliferation; Proteins; Reverse transcription; RNA polymerase; Scientific equipment and supplies industry; SIRT7; Succinylation; T cells; Thyroid cancer; Thyroid gland; Wound healing; Wounds and injuries; China; United States; United States > US; Japan; Anaplastic thyroid cancer; KIF23; Proliferation; SIRT7; Succinylation; Migration

This study was designed to investigate the regulatory effects of kinesin family member (KIF) 23 on anaplastic thyroid cancer (ATC) cell viability and migration and the underlying mechanism. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used to analyze the levels of KIF23...