Relationship between clinical outcomes and Dutch frailty score among elderly patients who underwent surgery for hip fracture

• Published in: Clinical interventions in aging Vol. 13; pp. 2481 - 2486
• Main Authors: Winters, A M, Hartog, L C, Roijen, Hif, Brohet, R M, Kamper, A M
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2018; Taylor & Francis Ltd; Dove Medical Press
• Subjects: Aged; Aged, 80 and over; Chronic obstructive pulmonary disease; Clinical outcomes; Elderly; Elderly patients; Female; Follow-Up Studies; Fractures (Injuries); Frailty; Frailty - classification; Frailty - complications; Functional decline; Geriatric Assessment - methods; Hip fracture; Hip Fractures - complications; Hip Fractures - surgery; Hospitals; Humans; Kaplan-Meier Estimate; Male; Medical research; Mortality; Netherlands; Older people; Original Research; Orthopedic surgery; Patient outcomes; Predictive Value of Tests; Prospective Studies; Risk Factors; Severity of Illness Index; Survival Rate; Netherlands; functional decline; mortality; geriatric patients; frailty assessment; orthopedic surgery
• ISSN: 1178-1998; 1176-9092; 1178-1998
• DOI: 10.2147/CIA.S181497

Frailty is a geriatric condition that is associated with an increased risk of mortality and functional decline. To date, mainly the Groningen Frailty Indicator (GFI) and Hospital Safety Management (VeiligheidsManagementSysteem [VMS]) frailty score are used to determine frailty in several hospitals in the Netherlands. However, it is yet unknown, which method has the best predictive value on clinical outcomes. The aim of this study was to investigate the predictive value of GFI and VMS on clinical outcomes among patients who underwent hip fracture surgery. This is a prospective observational cohort study. We selected all patients aged 70 years or higher, who underwent hip fracture surgery in our general hospital, between November 2014 and November 2015. Among all patients, VMS, GFI and Barthel-20 index (BI) were assessed. McNemar's paired test and Cohen's κ were used to examine the difference and the level of agreement between the two scoring methods. Kaplan-Meier and multivariable regression analyses were performed to determine overall survival and mortality, respectively, 3 years and 30 days after surgery. A total of 280 patients were included in the study. The median follow-up was 25 months. No systematic difference was found between the two methods ( =0.237), while a fair level of agreement could be measured (κ=0.363 [95% CI =0.23-50]). VMS showed a statistically significant difference in overall survival as compared to nonfrail patients (57 vs 80%, respectively [ <0.001] with an HR of 3.5 [95% CI =2.1-5.7; <0.001]). Classification according to GFI yielded a lower but still significant HR 2.3 (95% CI =1.2-4.1; =0.008). VMS can be used in classifying frailty, whereby VMS frailty score is associated with clinical outcomes as overall survival mortality in older patients with hip fracture and who underwent surgery.