pH-Responsive Super-Porous Hybrid Hydrogels for Gastroretentive Controlled-Release Drug Delivery

• Published in: Pharmaceutics Vol. 15; no. 3; p. 816
• Main Authors: Juthi, Ajkia Zaman, Li, Fenfen, Wang, Bo, Alam, Md Mofasserul, Talukder, Md Eman, Qiu, Bensheng
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.03.2023; MDPI
• Subjects: Controlled release technology; controlled-release drug delivery; Drug delivery systems; Ethanol; Gastrointestinal system; gastroretentive; Gels (Pharmacy); Hydrogels; Materials; Mechanical properties; Physiological aspects; Polymerization; Polymers; super-porous hybrid hydrogels; China; super-porous hybrid hydrogels; controlled-release drug delivery; gastroretentive

Super-porous hydrogels are considered a potential drug delivery network for the sedation of gastric mechanisms with retention windows in the abdomen and upper part of the gastrointestinal tract (GIT). In this study, a novel pH-responsive super-porous hybrid hydrogels (SPHHs) was synthesized from pec...