Current status of diagnosis and treatment of hepatic echinococcosis

Echinococcus granulosus(E.granulosus) and Echinococcus multilocularis(E.multilocularis) infections are the most common parasitic diseases that affect the liver.The disease course is typically slow and the patients tend to remain asymptomatic for many years.Often the diagnosis is incidental.Right upp...

Full description

Saved in:
Bibliographic Details
Published inWorld journal of hepatology Vol. 8; no. 28; pp. 1169 - 1181
Main Authors Mihmanli, Memmet, Idiz, Ufuk Oguz, Kaya, Cemal, Demir, Uygar, Bostanci, Ozgur, Omeroglu, Sinan, Bozkurt, Emre
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 08.10.2016
Subjects
Echinococcus
granulosus;Echinococcus
multilocularis;Liver;Ultrasonography;Albendazole
Review
Echinococcus multilocularis
Albendazole
Liver
Ultrasonography
Echinococcus granulosus
Online AccessGet full text
ISSN1948-5182
1948-5182
DOI10.4254/wjh.v8.i28.1169

Cover

More Information
Summary:Echinococcus granulosus(E.granulosus) and Echinococcus multilocularis(E.multilocularis) infections are the most common parasitic diseases that affect the liver.The disease course is typically slow and the patients tend to remain asymptomatic for many years.Often the diagnosis is incidental.Right upper quadrant abdominal pain,hepatitis,cholangitis,and anaphylaxis due to dissemination of the cyst are the main presenting symptoms.Ultrasonography is important in diagnosis.The World Health Organization classification,based on ultrasonographic findings,is used for staging of the disease and treatment selection.In addition to the imaging methods,immunological investigations are used to support the diagnosis.The available treatment options for E.granulosus infection include open surgery,percutaneous interventions,and pharmacotherapy.Aggressive surgery is the first-choice treatment for E.multilocularis infection,while pharmacotherapy is used as an adjunct to surgery.Due to a paucity of clinical studies,empirical evidence on the treatment of E.granulosus and E.multilocularis infections is largely lacking;there are no prominent and widely accepted clinical algorithms yet.In this article,we review the diagnosis and treatment of E.granulosus and E.multilocularis infections in the light of recent evidence.
Bibliography:Memmet Mihmanli;Ufuk Oguz Idiz;Cemal Kaya;Uygar Demir;Ozgur Bostanci;Sinan Omeroglu;Emre Bozkurt;Department of General Surgery,Sisli Hamidiye Etfal Training and Research Hospital
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Correspondence to: Memmet Mihmanli, MD, Professor, Department of General Surgery, Sisli Hamidiye Etfal Training and Research Hospital, Halaskargazi Caddesi, 34371 Istanbul, Turkey. mmihmanli@yahoo.com
Telephone: +90-53-22853159
Author contributions: Mihmanli M and Idiz UO contributed equally to this work, generated the figures and wrote the manuscript; Kaya C, Demir U, Bostanci O, Omeroglu S and Bozkurt E contributed to the writing of the manuscript; Mihmanli M designed the aim of the editorial and wrote the manuscript.
ISSN:1948-5182
1948-5182
DOI:10.4254/wjh.v8.i28.1169