Spontaneous rate of sister chromatid exchanges (SCEs) and BrdU dose-response relationships in mitotic chromosomes of goat (Capra hircus L.)

• Published in: Hereditas Vol. 124; no. 2; pp. 137 - 144
• Main Authors: di Berardino, Dino, Jovino, Valeria, Lioi, Maria Brigida, Scarfi, Maria Rosaria, Burguete, Isabel
• Format: Journal Article
• Language: English
• Published: Oxford, UK Munksgaard International Publishers 01.01.1996
• Subjects: Animals; Bromodeoxyuridine; Capra hircus; Chromosomes; Dose-Response Relationship, Drug; Goats - genetics; Mitosis - drug effects; Sister Chromatid Exchange

The spontaneous level of sister chromatid exchange (SCEs) in the goat, estimated by exposing peripheral blood lymphocytes to 0.1 μg/ml of 5‐bromodeoxyuridine (BrdU), was 3.28 ± 1.71 SCE/cell, 1.64 SCE/cell generation and 0.027 SCE/chromosome. The dose–response curve of SCE/cell, observed by exposing...