ECMO for Severe Acute Respiratory Distress Syndrome

To the Editor: In the trial conducted by Combes et al. (May 24 issue), 1 a large number of patients who had been randomly assigned to the control group later crossed over to receive extracorporeal membrane oxygenation (ECMO). The rate of the key secondary outcome (a composite of death or treatment f...

Full description

Saved in:
Bibliographic Details
Published inThe New England journal of medicine Vol. 379; no. 11; pp. 1090 - 1093
Main Authors Shanholtz, Carl, Reed, Robert M, Brower, Roy G, Patel, Brijesh V, Barrett, Nicholas A, Vuylsteke, Alain, Muñoz, Javier, Keough, Elena A, Visedo, Lourdes C, Combes, Alain, Slutsky, Arthur S, Brodie, Daniel, Hardin, C. Corey, Hibbert, Kathryn
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 13.09.2018
Subjects
Extracorporeal Membrane Oxygenation
Humans
Oxygenation
Patients
Respiration, Artificial
Respiratory distress syndrome
Respiratory Distress Syndrome, Adult
Respiratory therapy
Retrospective Studies
Online AccessGet full text

Cover

More Information
Summary:To the Editor: In the trial conducted by Combes et al. (May 24 issue), 1 a large number of patients who had been randomly assigned to the control group later crossed over to receive extracorporeal membrane oxygenation (ECMO). The rate of the key secondary outcome (a composite of death or treatment failure) was significantly lower in the ECMO group than in the control group. The conclusions of this analysis are problematic. First, despite the severity of the acute respiratory distress syndrome (ARDS) and the illness trajectory, the patients in the control group who crossed over were younger than those who did . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc1808731