Immunological changes after COVID-19 vaccination in an HIV-positive patient

•Vaccination is an essential and promising way to cope with the COVID-19 pandemic.•We report the case of an HIV-positive patient showing deterioration after vaccination.•Caution should be taken when vaccinating HIV-positive patients who are not on medication. Vaccination is an essential measure to s...

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Bibliographic Details
Published inInternational journal of infectious diseases Vol. 117; pp. 230 - 232
Main Authors Gong, Changlin, Song, Xiaojing, Li, Xiaoxia, Lu, Lianfeng, Li, Taisheng
Format Journal Article
LanguageEnglish
Published Canada Elsevier Ltd 01.04.2022
Published by Elsevier Ltd on behalf of International Society for Infectious Diseases
Elsevier
Subjects
CD4+ T cells
CD4-Positive T-Lymphocytes
Coronavirus disease 2019
COVID-19 - prevention & control
COVID-19 Vaccines
HIV Infections - complications
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Vaccination
Vaccine
Vaccine
Human immunodeficiency virus
Coronavirus disease 2019
CD4+ T cells
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Summary:•Vaccination is an essential and promising way to cope with the COVID-19 pandemic.•We report the case of an HIV-positive patient showing deterioration after vaccination.•Caution should be taken when vaccinating HIV-positive patients who are not on medication. Vaccination is an essential measure to stop the coronavirus disease 2019 (COVID-19) pandemic. We report a case of viral activation and CD4+ T cell loss in a treatment-naïve HIV-positive patient after receiving inactivated COVID-19 vaccine (Sinopharm). The vaccine should probably be given only to people living with HIV receiving antiretroviral therapy.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:1201-9712
1878-3511
1878-3511
DOI:10.1016/j.ijid.2021.08.039