Test-retest reliability and concurrent validity of knee extensor strength measured by a novel device incorporated into a weight stack machine vs. handheld and isokinetic dynamometry

• Published in: PloS one Vol. 19; no. 5; p. e0301872
• Main Authors: Sahu, Pradeep K, Goodstadt, Noel, Ramakrishnan, Arun, Silfies, Sheri P
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 22.05.2024; Public Library of Science (PLoS)
• Subjects: Adult; Arthritis; Biology and Life Sciences; Cardiovascular disease; Clinical medicine; Clinical trials; Comparative analysis; Correlation coefficient; Correlation coefficients; Cross correlation; Dynamometers; Engineering and Technology; Female; Humans; Injuries; Isometric Contraction - physiology; Knee; Knee - physiology; Knee - physiopathology; Knee Joint - physiology; Knee Joint - physiopathology; Male; Medicine and Health Sciences; Middle Aged; Muscle contraction; Muscle strength; Muscle Strength - physiology; Muscle Strength Dynamometer; Muscles; Osteoarthritis; Osteoarthritis, Knee - physiopathology; Physical therapy; Quadriceps muscle; Quadriceps Muscle - physiology; Reliability analysis; Reproducibility of Results; Research and Analysis Methods; Strength testing; Therapeutics, Physiological; Validity; Weight; Young Adult; United States > US
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0301872

The current clinical gold standard for assessing isometric quadriceps muscle strength is an isokinetic dynamometer (IKD). However, in clinics without an IKD, clinicians default to using handheld dynamometers (HHD), which are less reliable and accurate than the IKD, particularly for large muscle groups. A novel device (ND) was developed that locks the weight stack of weight machines, and measures forces applied to the machine, turning this equipment into an isometric dynamometer. The objectives of this study were to characterize the test-retest reliability of the ND, determine the within-day and between-days inter-rater reliability and concurrent validity compared with that of the HHD, in healthy volunteers (HV) and individuals with knee osteoarthritis (OA) for measuring knee extensors isometric muscle force. 29 healthy (age = 28.4 ± 7.4 years) and 15 knee OA (age = 37.6 ± 13.4 years) participants completed three maximum force isometric strength testing trials on dominant side knee extensor muscles on three devices (ND, HHD, and IKD) in two separate sessions by two raters. The maximum force (Fmax) produced, and the force-time series were recorded. Reliability and validity were assessed using Intraclass Correlation Coefficient (ICC), Bland-Altman Plots, Pearson's r, and cross-correlations. The ND demonstrated excellent test-retest reliability (ICC2,3 = 0.97). The within-day (ICC2,3 = 0.88) and between-day inter-rater reliability (ICC2,3 = 0.87) was good for HHD. The ND showed excellent within-day (ICC2,3 = 0.93) and good between-day (ICC2,3 = 0.89) inter-rater reliability. The Bland-Altman analysis revealed HHD systematic bias and underestimation of force particularly with quadriceps force values exceeding 450 N. Mean differences were found in maximum force between HHD vs. IKD (MDabs = 58 N, p < .001) but not the HHD vs. ND (MDabs = 24 N, p = .267) or ND vs. IKD (MDabs = 34 N, p = .051). The concurrent validity of Fmax (r = 0.81) and force-time curve correlation (0.96 ± 0.05) were the highest between the ND and IKD. The ND's test-retest reliability and concurrent validity make it a potential strength assessment tool with utility in physical therapy and fitness settings for large muscle groups such as the knee extensors.