The clinical and immunological spectrum of American cutaneous leishmaniasis

American cutaneous leishmaniasis is characterized by a spectrum of clinical manifestations. These include localized, often self-healing single lesions, intermediate forms which frequently produce mucosal lesions and often show exaggerated delayed-type hypersensitivity (DTH), and the rare diffuse cut...

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Published inTransactions of the Royal Society of Tropical Medicine and Hygiene Vol. 87; no. 4; pp. 444 - 448
Main Authors Convit, J., Ulrich, M., Fernández, C.T., Tapia, F.J., Cáceres-Dittmar, G., Castés, M., Rondón, A.J.
Format Journal Article Conference Proceeding
LanguageEnglish
Published Oxford Elsevier Ltd 01.07.1993
Royal Society of Tropical Medicine and Hygiene
Elsevier
Subjects
Animals
Antigens, Protozoan - immunology
Biological and medical sciences
Enzyme-Linked Immunosorbent Assay
Female
Human protozoal diseases
Humans
Hypersensitivity, Delayed - immunology
Infectious diseases
Leishmania
Leishmania mexicana - immunology
Leishmaniasis, Cutaneous - immunology
Leishmaniasis, Cutaneous - pathology
Leishmaniasis, Diffuse Cutaneous - immunology
Leishmaniasis, Mucocutaneous - immunology
Leshmaniasis
Lymphocyte Activation - immunology
Male
Medical sciences
Parasitic diseases
Protozoal diseases
Skin - immunology
Skin - pathology
Tropical medicine
South America
Venezuela
America
Infection
Human
Symptomatology
Skin disease
Protozoal disease
Immune response
Immunological investigation
Cellular immunity
Skin
Leishmaniasis
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Abstract American cutaneous leishmaniasis is characterized by a spectrum of clinical manifestations. These include localized, often self-healing single lesions, intermediate forms which frequently produce mucosal lesions and often show exaggerated delayed-type hypersensitivity (DTH), and the rare diffuse cutaneous leishmaniasis in which no reaction of protective cell-mediated immunity or DTH can be demonstrated. Clinical, pathological and immunological studies have begun to unravel some of the mechanisms associated with different disease manifestations, dependent on complex interactions between the host immune response, measured in terms of indices including lymphocyte subsets and lymphokines in vitro and within active lesions, and different species of Leishmania.
AbstractList American cutaneous leishmaniasis is characterized by a spectrum of clinical manifestations. These include localized, often self-healing single lesions, intermediate forms which frequently produce mucosal lesions and often show exaggerated delayed-type hypersensitivity (DTH), and the rare diffuse cutaneous leishmaniasis in which no reaction of protective cell-mediated immunity or DTH can be demonstrated. Clinical, pathological and immunological studies have begun to unravel some of the mechanisms associated with different disease manifestations, dependent on complex interactions between the host immune response, measured in terms of indices including lymphocyte subsets and lymphokines in vitro and within active lesions, and different species of Leishmania.
American cutaneous leishmaniasis is characterized by a spectrum of clinical manifestations. These include localized, often self-healing single lesions, intermediate forms which frequently produce mucosal lesions and often show exaggerated delayed-type hypersensitivity (DTH), and the rare diffuse cutaneous leishmaniasis in which no reaction of protective cell-mediated immunity or DTH can be demonstrated. Clinical, pathological and immunological studies have begun to unravel some of the mechanisms associated with different disease manifestations, dependent on complex interactions between the host immune response, measured in terms of indices including lymphocyte subsets and lymphokines in vitro and within active lesions, and different species of Leishmania.
Author Fernández, C.T.
Tapia, F.J.
Rondón, A.J.
Ulrich, M.
Castés, M.
Cáceres-Dittmar, G.
Convit, J.
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Cites_doi 10.1093/infdis/159.4.725
10.1016/0035-9203(80)90069-3
10.4049/jimmunol.135.6.4144
10.1093/infdis/160.1.104
10.4269/ajtmh.1987.37.520
10.1016/0090-1229(83)90068-5
10.1016/0001-706X(91)90078-X
10.1016/S0167-5699(05)80017-9
10.1128/JCM.26.6.1207-1213.1988
10.1016/0035-9203(83)90185-2
10.1056/NEJM198202183060702
10.4269/ajtmh.1991.45.281
10.1016/S0140-6736(87)90116-4
10.1016/0035-9203(87)90424-X
10.1016/0035-9203(86)90243-9
10.1111/j.1365-2249.1990.tb05182.x
10.1016/0035-9203(72)90306-9
10.1016/0167-5699(92)90110-S
10.4269/ajtmh.1988.39.179
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Issue 4
Keywords Infection
Human
Symptomatology
Skin disease
Protozoal disease
Immune response
Immunological investigation
Cellular immunity
Skin
Leishmaniasis
Language English
License CC BY 4.0
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Address for correspondence: Dr Jacinto Convit, Instituto de Biomedicina, Apartado 4043, Caracas 1010A, Venezuela.
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References Castés, Cabrera, Trujillo, Convit (BIB5) 1988; 26
Saravia, Valderrama, Labrada, Holguin, Navas, Palma, Weigle (BIB24) 1989; 159
Locksley, Scott (BIB17) 1991
Conceiçao-Silva, Dorea, Pirmez, Shubach, Coutinho (BIB6) 1990; 79
Convit, Castellanos, Rondón, Pinardi, Ulrich, Castés, Bloom, Garcia (BIB12) 1987; i
Costa, Netto, Vale, Osaki, Tada, Marsden (BIB14) 1987; 81
Convit, Ulrich, Aranzazu, Castellanos, Pinardi, Reyes (BIB11) 1986; 57
Castés, Agnelli, Verde, Rondón (BIB3) 1983; 27
Marsden (BIB18) 1986; 80
Bloom, Salgame, Diamond (BIB1) 1992; 13
Convit, Pinardi, Rondón (BIB10) 1972; 66
Lainson (BIB16) 1983; 77
Gutierrez, Salinas, Palma, Valderrama, Santrich, Saravia (BIB15) 1991; 45
Martínez-Arends, Tapia, Cáceres-Dittmar, Mosca, Valecillos, Convit (BIB19) 1991; 49
Modlin, Tapia, Bloom, Gallinoto, Castés, Rondón, Rea, Convit (BIB20) 1985; 60
Convit, Pinardi (BIB9) 1974
Convit, Castellanos, Ulrich, Castés, Rondón, Pinardi, Rodríguez, Bloom, Formica, Valecillos, Bretaña (BIB13) 1989; 160
Castés, Agnelli, Rondón (BIB4) 1984; 57
Petersen, Neva, Oster, Bogaert Diaz (BIB21) 1982; 306
Ridley (BIB23) 1980; 74
Convit (BIB7) 1974; 12
Convit, Lapenta (BIB8) 1948; 18
Carvalho, Johnson, Barreto, Marsden, Costa, Reed, Rocha (BIB2) 1985; 153
Ulrich, Centeno, Mattout, Convit (BIB25) 1988; 39
Rada, Trujillo, Castellanos, Convit (BIB22) 1987; 37
Rada (10.1016/0035-9203(93)90030-T_BIB22) 1987; 37
Convit (10.1016/0035-9203(93)90030-T_BIB8) 1948; 18
Lainson (10.1016/0035-9203(93)90030-T_BIB16) 1983; 77
Convit (10.1016/0035-9203(93)90030-T_BIB7) 1974; 12
Convit (10.1016/0035-9203(93)90030-T_BIB12) 1987; i
Petersen (10.1016/0035-9203(93)90030-T_BIB21) 1982; 306
Convit (10.1016/0035-9203(93)90030-T_BIB11) 1986; 57
Castés (10.1016/0035-9203(93)90030-T_BIB5) 1988; 26
Locksley (10.1016/0035-9203(93)90030-T_BIB17) 1991
Convit (10.1016/0035-9203(93)90030-T_BIB13) 1989; 160
Costa (10.1016/0035-9203(93)90030-T_BIB14) 1987; 81
Martínez-Arends (10.1016/0035-9203(93)90030-T_BIB19) 1991; 49
Marsden (10.1016/0035-9203(93)90030-T_BIB18) 1986; 80
Saravia (10.1016/0035-9203(93)90030-T_BIB24) 1989; 159
Ulrich (10.1016/0035-9203(93)90030-T_BIB25) 1988; 39
Carvalho (10.1016/0035-9203(93)90030-T_BIB2) 1985; 153
Castés (10.1016/0035-9203(93)90030-T_BIB4) 1984; 57
Bloom (10.1016/0035-9203(93)90030-T_BIB1) 1992; 13
Modlin (10.1016/0035-9203(93)90030-T_BIB20) 1985; 60
Conceiçao-Silva (10.1016/0035-9203(93)90030-T_BIB6) 1990; 79
Ridley (10.1016/0035-9203(93)90030-T_BIB23) 1980; 74
Convit (10.1016/0035-9203(93)90030-T_BIB9) 1974
Castés (10.1016/0035-9203(93)90030-T_BIB3) 1983; 27
Convit (10.1016/0035-9203(93)90030-T_BIB10) 1972; 66
Gutierrez (10.1016/0035-9203(93)90030-T_BIB15) 1991; 45
References_xml – volume: 160
  start-page: 104
  year: 1989
  end-page: 115
  ident: BIB13
  article-title: Immunotherapy of localized, intermediate, and diffuse forms of American cutaneous leishmaniasis
  publication-title: Journal of Infectious Diseases
  contributor:
    fullname: Bretaña
– volume: 81
  start-page: 606
  year: 1987
  ident: BIB14
  article-title: Spontaneous healing of cutaneous
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  contributor:
    fullname: Marsden
– volume: 13
  start-page: 131
  year: 1992
  end-page: 136
  ident: BIB1
  article-title: Revisiting and revising suppressor cells
  publication-title: Immunology Today
  contributor:
    fullname: Diamond
– volume: 57
  start-page: 263
  year: 1986
  end-page: 273
  ident: BIB11
  article-title: The development of a vaccination model using two microorganisms and its application in leprosy and leishmaniasis
  publication-title: Leprosy Review
  contributor:
    fullname: Reyes
– start-page: A58
  year: 1991
  end-page: A61
  ident: BIB17
  article-title: Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function
  publication-title: Immunoparasitology Today
  contributor:
    fullname: Scott
– volume: 153
  start-page: 4144
  year: 1985
  end-page: 4148
  ident: BIB2
  article-title: Cell-mediated immunity in American cutaneous leishmaniasis
  publication-title: Journal of Immunology
  contributor:
    fullname: Rocha
– volume: 57
  start-page: 279
  year: 1984
  end-page: 286
  ident: BIB4
  article-title: Mechanisms associated with immunoregulation in human American cutaneous leishmaniasis
  publication-title: Clinical and Experimental Immunology
  contributor:
    fullname: Rondón
– volume: 79
  start-page: 221
  year: 1990
  end-page: 226
  ident: BIB6
  article-title: Quantitative study of
  publication-title: Clinical and Experimental Immunology
  contributor:
    fullname: Coutinho
– volume: 66
  start-page: 603
  year: 1972
  end-page: 610
  ident: BIB10
  article-title: Diffuse cutaneous leishmaniasis: a disease due to an immunological defect of the host
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  contributor:
    fullname: Rondón
– volume: 18
  start-page: 153
  year: 1948
  ident: BIB8
  article-title: Sobre un caso de leishmaniasis diseminada
  publication-title: Revista Policlínica de Caracas
  contributor:
    fullname: Lapenta
– volume: 306
  start-page: 387
  year: 1982
  end-page: 390
  ident: BIB21
  article-title: Specific inhibition of lymphocyte-proliferation responses by adherent suppressor cells in diffuse cutaneous leishmaniasis
  publication-title: New England Journal of Medicine
  contributor:
    fullname: Bogaert Diaz
– volume: 37
  start-page: 520
  year: 1987
  end-page: 524
  ident: BIB22
  article-title: Gamma interferon production induced by antigens in patients with leprosy and American cutaneous leishmaniasis
  publication-title: American Journal of Tropical Medicine and Hygiene
  contributor:
    fullname: Convit
– volume: 45
  start-page: 281
  year: 1991
  end-page: 289
  ident: BIB15
  article-title: Correlation between histopathology, clinical presentation, and evolution in
  publication-title: American Journal of Tropical Medicine and Hygiene
  contributor:
    fullname: Saravia
– volume: 159
  start-page: 725
  year: 1989
  end-page: 735
  ident: BIB24
  article-title: The relationship of
  publication-title: Journal of Infectious Diseases
  contributor:
    fullname: Weigle
– volume: 26
  start-page: 1207
  year: 1988
  end-page: 1213
  ident: BIB5
  article-title: T-cell subpopulations, expression of interleukin-2 receptor, and production of interleukin-2 and gamma interferon in human American cutaneous leishmaniasis
  publication-title: Journal of Clinical Microbiology
  contributor:
    fullname: Convit
– volume: 39
  start-page: 179
  year: 1988
  end-page: 184
  ident: BIB25
  article-title: Serological patterns and specificity in American cutaneous leishmaniasis
  publication-title: American Journal of Tropical Medicine and Hygiene
  contributor:
    fullname: Convit
– volume: 12
  start-page: 187
  year: 1974
  end-page: 195
  ident: BIB7
  article-title: Leprosy and leishmaniasis. Similar clinical-immunological-pathological models
  publication-title: Ethiopian Medical Journal
  contributor:
    fullname: Convit
– volume: 49
  start-page: 271
  year: 1991
  end-page: 280
  ident: BIB19
  article-title: Immunocytochemical characterization of immune cells in lesions of American cutaneous leishmaniasis using novel T cell markers
  publication-title: Acta Tropica
  contributor:
    fullname: Convit
– volume: 27
  start-page: 176
  year: 1983
  end-page: 186
  ident: BIB3
  article-title: Characterization of the cellular immune response in American cutaneous leishmaniasis
  publication-title: Clinical Immunology and Immunopathology
  contributor:
    fullname: Rondón
– volume: i
  start-page: 401
  year: 1987
  end-page: 405
  ident: BIB12
  article-title: Immunotherapy versus chemotherapy in localised cutaneous leishmaniasis
  publication-title: Lancet
  contributor:
    fullname: Garcia
– volume: 77
  start-page: 569
  year: 1983
  end-page: 595
  ident: BIB16
  article-title: The American leishmaniases: some observations on their ecology and epidemiology
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  contributor:
    fullname: Lainson
– volume: 74
  start-page: 515
  year: 1980
  end-page: 521
  ident: BIB23
  article-title: A histological classification of cutaneous leishmaniasis and its geographical expression
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  contributor:
    fullname: Ridley
– start-page: 159
  year: 1974
  end-page: 169
  ident: BIB9
  article-title: Cutaneous leishmaniasis. The clinical and immunological spectrum in South America
  publication-title: Trypanosomiasis and Leishmaniasis with Special Reference to Chagas' Disease
  contributor:
    fullname: Pinardi
– volume: 80
  start-page: 859
  year: 1986
  end-page: 876
  ident: BIB18
  article-title: Mucosal leishmaniasis (‘espundia’ Escomel, 1911)
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  contributor:
    fullname: Marsden
– volume: 60
  start-page: 241
  year: 1985
  end-page: 248
  ident: BIB20
  article-title:
  publication-title: Clinical and Experimental Immunology
  contributor:
    fullname: Convit
– volume: 159
  start-page: 725
  year: 1989
  ident: 10.1016/0035-9203(93)90030-T_BIB24
  article-title: The relationship of Leishmania braziliensis subspecies and immune response to disease expression in New World leishmaniasis
  publication-title: Journal of Infectious Diseases
  doi: 10.1093/infdis/159.4.725
  contributor:
    fullname: Saravia
– volume: 74
  start-page: 515
  year: 1980
  ident: 10.1016/0035-9203(93)90030-T_BIB23
  article-title: A histological classification of cutaneous leishmaniasis and its geographical expression
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  doi: 10.1016/0035-9203(80)90069-3
  contributor:
    fullname: Ridley
– volume: 153
  start-page: 4144
  year: 1985
  ident: 10.1016/0035-9203(93)90030-T_BIB2
  article-title: Cell-mediated immunity in American cutaneous leishmaniasis
  publication-title: Journal of Immunology
  doi: 10.4049/jimmunol.135.6.4144
  contributor:
    fullname: Carvalho
– start-page: 159
  year: 1974
  ident: 10.1016/0035-9203(93)90030-T_BIB9
  article-title: Cutaneous leishmaniasis. The clinical and immunological spectrum in South America
  contributor:
    fullname: Convit
– volume: 160
  start-page: 104
  year: 1989
  ident: 10.1016/0035-9203(93)90030-T_BIB13
  article-title: Immunotherapy of localized, intermediate, and diffuse forms of American cutaneous leishmaniasis
  publication-title: Journal of Infectious Diseases
  doi: 10.1093/infdis/160.1.104
  contributor:
    fullname: Convit
– volume: 37
  start-page: 520
  year: 1987
  ident: 10.1016/0035-9203(93)90030-T_BIB22
  article-title: Gamma interferon production induced by antigens in patients with leprosy and American cutaneous leishmaniasis
  publication-title: American Journal of Tropical Medicine and Hygiene
  doi: 10.4269/ajtmh.1987.37.520
  contributor:
    fullname: Rada
– volume: 27
  start-page: 176
  year: 1983
  ident: 10.1016/0035-9203(93)90030-T_BIB3
  article-title: Characterization of the cellular immune response in American cutaneous leishmaniasis
  publication-title: Clinical Immunology and Immunopathology
  doi: 10.1016/0090-1229(83)90068-5
  contributor:
    fullname: Castés
– volume: 49
  start-page: 271
  year: 1991
  ident: 10.1016/0035-9203(93)90030-T_BIB19
  article-title: Immunocytochemical characterization of immune cells in lesions of American cutaneous leishmaniasis using novel T cell markers
  publication-title: Acta Tropica
  doi: 10.1016/0001-706X(91)90078-X
  contributor:
    fullname: Martínez-Arends
– start-page: A58
  year: 1991
  ident: 10.1016/0035-9203(93)90030-T_BIB17
  article-title: Helper T-cell subsets in mouse leishmaniasis: induction, expansion and effector function
  publication-title: Immunoparasitology Today
  doi: 10.1016/S0167-5699(05)80017-9
  contributor:
    fullname: Locksley
– volume: 12
  start-page: 187
  year: 1974
  ident: 10.1016/0035-9203(93)90030-T_BIB7
  article-title: Leprosy and leishmaniasis. Similar clinical-immunological-pathological models
  publication-title: Ethiopian Medical Journal
  contributor:
    fullname: Convit
– volume: 57
  start-page: 279
  year: 1984
  ident: 10.1016/0035-9203(93)90030-T_BIB4
  article-title: Mechanisms associated with immunoregulation in human American cutaneous leishmaniasis
  publication-title: Clinical and Experimental Immunology
  contributor:
    fullname: Castés
– volume: 26
  start-page: 1207
  year: 1988
  ident: 10.1016/0035-9203(93)90030-T_BIB5
  article-title: T-cell subpopulations, expression of interleukin-2 receptor, and production of interleukin-2 and gamma interferon in human American cutaneous leishmaniasis
  publication-title: Journal of Clinical Microbiology
  doi: 10.1128/JCM.26.6.1207-1213.1988
  contributor:
    fullname: Castés
– volume: 18
  start-page: 153
  year: 1948
  ident: 10.1016/0035-9203(93)90030-T_BIB8
  article-title: Sobre un caso de leishmaniasis diseminada
  publication-title: Revista Policlínica de Caracas
  contributor:
    fullname: Convit
– volume: 77
  start-page: 569
  year: 1983
  ident: 10.1016/0035-9203(93)90030-T_BIB16
  article-title: The American leishmaniases: some observations on their ecology and epidemiology
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  doi: 10.1016/0035-9203(83)90185-2
  contributor:
    fullname: Lainson
– volume: 306
  start-page: 387
  year: 1982
  ident: 10.1016/0035-9203(93)90030-T_BIB21
  article-title: Specific inhibition of lymphocyte-proliferation responses by adherent suppressor cells in diffuse cutaneous leishmaniasis
  publication-title: New England Journal of Medicine
  doi: 10.1056/NEJM198202183060702
  contributor:
    fullname: Petersen
– volume: 45
  start-page: 281
  year: 1991
  ident: 10.1016/0035-9203(93)90030-T_BIB15
  article-title: Correlation between histopathology, clinical presentation, and evolution in Leishmania braziliensis infection
  publication-title: American Journal of Tropical Medicine and Hygiene
  doi: 10.4269/ajtmh.1991.45.281
  contributor:
    fullname: Gutierrez
– volume: i
  start-page: 401
  year: 1987
  ident: 10.1016/0035-9203(93)90030-T_BIB12
  article-title: Immunotherapy versus chemotherapy in localised cutaneous leishmaniasis
  publication-title: Lancet
  doi: 10.1016/S0140-6736(87)90116-4
  contributor:
    fullname: Convit
– volume: 57
  start-page: 263
  issue: supplement 2
  year: 1986
  ident: 10.1016/0035-9203(93)90030-T_BIB11
  article-title: The development of a vaccination model using two microorganisms and its application in leprosy and leishmaniasis
  publication-title: Leprosy Review
  contributor:
    fullname: Convit
– volume: 81
  start-page: 606
  year: 1987
  ident: 10.1016/0035-9203(93)90030-T_BIB14
  article-title: Spontaneous healing of cutaneous Leishmania braziliensis braziliensis ulcers
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  doi: 10.1016/0035-9203(87)90424-X
  contributor:
    fullname: Costa
– volume: 80
  start-page: 859
  year: 1986
  ident: 10.1016/0035-9203(93)90030-T_BIB18
  article-title: Mucosal leishmaniasis (‘espundia’ Escomel, 1911)
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  doi: 10.1016/0035-9203(86)90243-9
  contributor:
    fullname: Marsden
– volume: 79
  start-page: 221
  year: 1990
  ident: 10.1016/0035-9203(93)90030-T_BIB6
  article-title: Quantitative study of Leishmania braziliensis braziliensis reactive T cells in peripheral blood and in the lesions of patients with American cutaneous leishmaniasis
  publication-title: Clinical and Experimental Immunology
  doi: 10.1111/j.1365-2249.1990.tb05182.x
  contributor:
    fullname: Conceiçao-Silva
– volume: 66
  start-page: 603
  year: 1972
  ident: 10.1016/0035-9203(93)90030-T_BIB10
  article-title: Diffuse cutaneous leishmaniasis: a disease due to an immunological defect of the host
  publication-title: Transactions of the Royal Society of Tropical Medicine and Hygiene
  doi: 10.1016/0035-9203(72)90306-9
  contributor:
    fullname: Convit
– volume: 60
  start-page: 241
  year: 1985
  ident: 10.1016/0035-9203(93)90030-T_BIB20
  article-title: In situ characterization of the cellular immune response in American cutaneous leishmaniasis
  publication-title: Clinical and Experimental Immunology
  contributor:
    fullname: Modlin
– volume: 13
  start-page: 131
  year: 1992
  ident: 10.1016/0035-9203(93)90030-T_BIB1
  article-title: Revisiting and revising suppressor cells
  publication-title: Immunology Today
  doi: 10.1016/0167-5699(92)90110-S
  contributor:
    fullname: Bloom
– volume: 39
  start-page: 179
  year: 1988
  ident: 10.1016/0035-9203(93)90030-T_BIB25
  article-title: Serological patterns and specificity in American cutaneous leishmaniasis
  publication-title: American Journal of Tropical Medicine and Hygiene
  doi: 10.4269/ajtmh.1988.39.179
  contributor:
    fullname: Ulrich
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Snippet American cutaneous leishmaniasis is characterized by a spectrum of clinical manifestations. These include localized, often self-healing single lesions,...
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SubjectTerms Animals
Antigens, Protozoan - immunology
Biological and medical sciences
Enzyme-Linked Immunosorbent Assay
Female
Human protozoal diseases
Humans
Hypersensitivity, Delayed - immunology
Infectious diseases
Leishmania
Leishmania mexicana - immunology
Leishmaniasis, Cutaneous - immunology
Leishmaniasis, Cutaneous - pathology
Leishmaniasis, Diffuse Cutaneous - immunology
Leishmaniasis, Mucocutaneous - immunology
Leshmaniasis
Lymphocyte Activation - immunology
Male
Medical sciences
Parasitic diseases
Protozoal diseases
Skin - immunology
Skin - pathology
Tropical medicine
Title The clinical and immunological spectrum of American cutaneous leishmaniasis
URI https://dx.doi.org/10.1016/0035-9203(93)90030-T
https://api.istex.fr/ark:/67375/HXZ-SHD9HPPB-B/fulltext.pdf
https://www.ncbi.nlm.nih.gov/pubmed/8249076
https://search.proquest.com/docview/16853802
https://search.proquest.com/docview/76083075
Volume 87
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