Tumor lysis syndrome in premature infant prompting early resection of a large sacrococcygeal teratoma: a case report

Background Sacrococcygeal teratomas (SCTs) are the most common congenital neoplasm and often require resection soon after birth. There are rare reports of cardiac arrest during surgery due to manipulation of the tumor triggering secondary necrosis and hyperkalemia. Case presentation This case descri...

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Bibliographic Details
Published inBMC pediatrics Vol. 23; no. 1; pp. 1 - 6
Main Authors Dey, Aditi, Wyrebek, Rita, Torres, Loraine, Escoto, Danilo, Shakeel, Fauzia, Mayer, Jennifer
Format Journal Article
LanguageEnglish
Published London BioMed Central Ltd 02.09.2023
BioMed Central
BMC
Subjects
Ablation
Anemia
Apoptosis
Care and treatment
Case Report
Case reports
Chemotherapy
Diagnosis
Glucocorticoids
Health aspects
Hemorrhage
Hyperkalemia
Hypocalcemia
Infants (Premature)
Medical prognosis
Mortality
Newborn babies
Pediatrics
Pelvis
Potassium
Premature babies
Premature birth
Premature infant
Premature neonates
Rasburicase
Steroids
Surgery
Teratoma
Tumor lysis syndrome
Tumors
Ultrasonic imaging
Vagina
United States
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Summary:Background Sacrococcygeal teratomas (SCTs) are the most common congenital neoplasm and often require resection soon after birth. There are rare reports of cardiac arrest during surgery due to manipulation of the tumor triggering secondary necrosis and hyperkalemia. Case presentation This case describes a very preterm infant with a SCT who develops spontaneous preoperative tumor lysis syndrome (TLS). The medical team utilized rasburicase and the patient underwent total gross resection at 40 h of life. Conclusions We emphasize the importance of the early recognition and management of tumor lysis syndrome in SCT with rasburicase, aggressive management of hyperkalemia and consideration of early resection of SCTs even in the case of a very premature infant. Keywords: Glucocorticoids, Premature infant, Premature neonates, Rasburicase, Hyperkalemia, Tumor lysis syndrome, Sacrococcygeal teratoma, Neonate
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ObjectType-Report-1
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ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-023-04193-w