What Are the Unanswered Questions and Unmet Needs in Inflammatory Bowel Disease Management in Asia?

• Published in: Chinese medical journal Vol. 130; no. 22; pp. 2647 - 2649
• Main Authors: Li, Yue, Qian, Jia-Ming
• Format: Journal Article
• Language: English
• Published: China Medknow Publications and Media Pvt. Ltd 20.11.2017; Lippincott Williams & Wilkins Ovid Technologies; Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730, China; Medknow Publications & Media Pvt Ltd; Wolters Kluwer
• Subjects: Asia; Asia; Crohn's Disease; Gastrointestinal Tract; Inflammatory Bowel Disease; Biomarkers; Care and treatment; Clinical trials; Crohns disease; Disease Management; Endoscopy; Epidemiology; Gastroenterology; Health Services Needs and Demand; Humans; Inflammation; Inflammatory bowel disease; Inflammatory Bowel Diseases; Medical imaging; NMR; Nuclear magnetic resonance; Pathogenesis; Patients; Quality of Life; Asia; China; Crohn's Disease; Inflammatory Bowel Disease; Asia; Gastrointestinal Tract
• ISSN: 0366-6999; 2542-5641
• DOI: 10.4103/0366-6999.218018

A comprehensive predicting model using a combination of clinical, genetic, microbiotic factors and biomarkers will ideally resolve this unanswered question. [...]early introduction of disease-modifying anti-IBD drugs to patients with progressive predictors might bring greater chance to reach the target and prevent progression to bowel damage and disabling disease. There is a huge potential for variation in inflammatory response from patient to patient and within a single patient over time and then in response to different treatments. [...]patients enrolled in randomized controlled trials do not represent the IBD patient population due to strict inclusion criteria. Dissemination of standard and advance care of IBD across Asian countries still remains to be an unsolved question. [...]in this era of increasing complexity of care, education of patients to involve them in a well-informed decision-making process should also be encouraged. [...]although there are many unanswered questions and unmet needs in IBD management in Asia, looking back from where we set off, we are on a journey to better and greater. 1.