Chromatography in characterization of polysaccharides from medicinal plants and fungi

Polysaccharides isolated from medicinal plants and fungi exhibit multiple pharmacological activities. The biological activities of polysaccharides depend on their chemical characteristics. However, characterization of polysaccahrides is a challenge because of their complicated structure and macromol...

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Bibliographic Details
Published inJournal of separation science Vol. 36; no. 1; pp. 1 - 19
Main Authors Hu, De-jun, Cheong, Kit-leong, Zhao, Jing, Li, Shao-ping
Format Journal Article
LanguageEnglish
Published Weinheim Blackwell Publishing Ltd 01.01.2013
Wiley
Wiley Subscription Services, Inc
Subjects
Biochemistry
Biological and medical sciences
Characterization
Chromatography
Chromatography, High Pressure Liquid
Fungi
Fungi - chemistry
General pharmacology
Herbal medicine
Medical sciences
Medicinal fungus
Medicinal plants
Molecular Weight
Pharmacognosy. Homeopathy. Health food
Pharmacology
Pharmacology. Drug treatments
Plants, Medicinal - chemistry
Polysaccharides
Polysaccharides - chemistry
Polysaccharides - isolation & purification
Quality control
Ultra performance liquid chromatography
Medicinal plants
Chemical analysis
Pharmacognosy
HPLC chromatography
Review
Derivatization
Gel permeation chromatography
Medicinal plant
Characterization
Fungi
Hydrolysis
Thin layer chromatography
Gas chromatography
Polysaccharides
Medicinal fungus
Quality control
Plant origin
Detection
Polysaccharide
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Summary:Polysaccharides isolated from medicinal plants and fungi exhibit multiple pharmacological activities. The biological activities of polysaccharides depend on their chemical characteristics. However, characterization of polysaccahrides is a challenge because of their complicated structure and macromolecular mass. In this review, chromatography in characterization of polysaccharides, including physicochemical characterization (purity, molecular mass, and distribution), structural characterization (constituent monosaccharide composition and the ratio, the features of glycosidic linkages), and fingerprint of polysaccharides (acidic and enzymatic hydrolysates), from medicinal plants and fungi were reviewed and discussed according to the publications collected in Web of Science since 2007. The perspective for characterization of polysaccharides has also been described.
Bibliography:ark:/67375/WNG-GVW0045L-8
National Natural Science Foundation of China - No. 30928033
ArticleID:JSSC3105
University of Macau - No. UL015/09-Y4; No. MYRG140 (Y1-Y4)-ICMS12
Science and Technology Development Fund of Macau - No. 059/2011/A3
istex:AAAED2C419E03EA574CA0795C950BFAB6C01A503
These authors contributed equally to this work.
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ISSN:1615-9306
1615-9314
DOI:10.1002/jssc.201200874