Phenotypic Features and Salivary Parameters in Patients with Ectodermal Dysplasia: Report of Three Cases

Ectodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. Addi...

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Published inCase reports in dentistry Vol. 2018; no. 2018; pp. 1 - 8
Main Authors Salgado, Miguel Angel Castillo, Rocha, João Carlos da, Amorim, José Benedito Oliveira, Giannasi, Lilian Chrystiane, Sichi, Luigi Giovanni Bernardo, Gomes, Mônica Fernandes, Koga-Ito, Cristiane Yumi
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2018
Hindawi
Hindawi Limited
Wiley
Subjects
Aesthetics
Candida albicans
Care and treatment
Case Report
Case reports
Dental caries
Dental enamel
Dentistry
Dentures
Development and progression
Disease susceptibility
Dysplasia
Ectoderm
Ectodermal dysplasia
Genes
Genetic aspects
Health aspects
Mastication
Medical research
Microbiology
Microbiota
Microbiota (Symbiotic organisms)
Microorganisms
Mutation
Patients
Salivary gland
Self esteem
Streptococcus infections
Streptococcus mutans
Teeth
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Summary:Ectodermal dysplasia (ED) is a rare hereditary disorder affecting the development of ectoderm-derived organs and tissues. The aim of this study was to describe phenotypic features and the therapeutic approach in dentistry among three patients with ED, correlating their data with the literature. Additionally, to investigate the salivary gland disorders and their impacts on oral microbiota, we performed salivary tests, including salivary flow rate, salivary buffering capacity, and concentration levels of mutans streptococci, lactobacilli, and yeasts. All patients presented oligodontia, resulting in a significant masticatory dysfunction and aesthetic impairment. The counts of mutans streptococci n=3 and yeasts n=2 were high; on the other hand, the count of lactobacilli n=3 was low. Therefore, salivary and microbiological tests showed that the patients with ED, particularly the hypohidrotic type, presented a high risk of enamel caries and susceptibility to oral infections, which may be likely triggered by reduction of salivary flow and/or possible immunological disorders.
Bibliography:Academic Editor: Luis M. J. Gutierrez
ISSN:2090-6447
2090-6455
DOI:10.1155/2018/2409212