Protracted Febrile Myalgia Syndrome in a Japanese Patient with Fasciitis Detected on MRI

Protracted febrile myalgia syndrome (PFMS) is a rare manifestation of familial Mediterranean fever characterized by prolonged severe myalgia. We herein describe a case of PFMS with fasciitis on magnetic resonance imaging. The response to corticosteroid therapy was prompt, as is typical for PFMS. An...

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Bibliographic Details
Published inInternal Medicine Vol. 53; no. 24; pp. 2817 - 2819
Main Authors Fujikawa, Keita, Migita, Kiyoshi, Tsukada, Toshiaki, Kawakami, Atsushi, Eguchi, Katsumi
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 01.01.2014
Subjects
autoinflammatory disease
familial Mediterranean fever
Familial Mediterranean Fever - complications
Familial Mediterranean Fever - diagnosis
Familial Mediterranean Fever - genetics
Fasciitis - complications
Fasciitis - diagnosis
Fasciitis - drug therapy
Glucocorticoids - therapeutic use
Humans
Japan
Male
MRI
Myalgia - diagnosis
Myalgia - drug therapy
Myalgia - etiology
Prednisolone - therapeutic use
protracted febrile myalgia syndrome
Treatment Outcome
Young Adult
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Summary:Protracted febrile myalgia syndrome (PFMS) is a rare manifestation of familial Mediterranean fever characterized by prolonged severe myalgia. We herein describe a case of PFMS with fasciitis on magnetic resonance imaging. The response to corticosteroid therapy was prompt, as is typical for PFMS. An MEFV gene analysis revealed the patient to be homozygous for E148Q and compound heterozygous for P369S-R408Q. This is the first case report of a Japanese patient with PFMS. MRI findings may help to diagnose such cases.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.53.2871