Panel discussion review: session four - assessing biological plausibility of epidemiological findings in air pollution research

In December 2006, the U.S. Environmental Protection Agency (EPA) sponsored a 2-day workshop on "Interpretation of Epidemiologic Studies of Multipollutant Exposure and Health Effects" in Chapel Hill, NC. The final session at this workshop was devoted to assessing the biological plausibility...

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Bibliographic Details
Published inJournal of exposure science & environmental epidemiology Vol. 17; no. S2; pp. S97 - S105
Main Authors Brown, James S, Graham, Judith A, Chen, Lung Chi, Postlethwait, Edward M, Ghio, Andrew J, Foster, W Michael, Gordon, Terry
Format Journal Article
LanguageEnglish
Published United States Nature Publishing Group 01.12.2007
Subjects
Air pollution
Air Pollution - adverse effects
Air Pollution - analysis
Air Pollution - prevention & control
Criteria
Data Interpretation, Statistical
Environmental Exposure - adverse effects
Environmental Exposure - analysis
Environmental Exposure - prevention & control
Environmental Health - legislation & jurisprudence
Environmental Health - methods
Environmental Health - standards
Environmental protection
Epidemiologic Studies
Epidemiology
Exposure
Humans
Models, Biological
North Carolina
Pollutants
Pollution research
Pollution studies
Research - trends
Research Design
Risk Assessment
United States
United States Environmental Protection Agency
Workshops
North Carolina
United States
USA
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Summary:In December 2006, the U.S. Environmental Protection Agency (EPA) sponsored a 2-day workshop on "Interpretation of Epidemiologic Studies of Multipollutant Exposure and Health Effects" in Chapel Hill, NC. The final session at this workshop was devoted to assessing the biological plausibility of epidemiological findings with regard to criteria air pollutants. The presentations and the panel contributions of this last session primarily focused on controlled exposure studies and led to wide-ranging discussions, some of which were provocative. The panel summary provides some guidance to future evaluations of the biological plausibility of the epidemiological reports on criteria pollutants and is intended to stimulate thinking, without drawing any definitive conclusions. This paper does not approach, nor was it intended to approach, the more formal analytical approach such as that used in EPA's development of its Science Assessment Document for the criteria pollutants.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:1559-0631
1559-064X
DOI:10.1038/sj.jes.7500632