Development of a Bacteriophage Complex with Superhydrophilic and Superhydrophobic Nanotextured Surfaces of Metals Preventing Healthcare-Associated Infections (HAI)

We studied antibacterial properties of organo-inorganic hybrid coatings on the AMg2 aluminum alloy including superhydrophilic and superhydrophobic nanotextured metal substrates with applied bacteriophage particles. Bactericidal activity of surfaces after artificial contamination with a bacterial sus...

Full description

Saved in:
Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 167; no. 4; pp. 500 - 503
Main Authors Kaminskii, V. V., Aleshkin, A. V., Zul’karneev, E. R., Zatevalov, A. M., Kiseleva, I. A., Efimova, O. G., Emelyanenko, K. A., Emelyanenko, A. M., Boinovich, L. B.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.08.2019
Springer
Springer Nature B.V
Subjects
Alloys
Aluminum
Analysis
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antibacterial agents
Bactericidal activity
Bacteriophages - chemistry
Bacteriophages - physiology
Biomedical and Life Sciences
Biomedicine
Cell Biology
Colonization
Contamination
Cross Infection - prevention & control
Disease transmission
Health aspects
Hydrophobic and Hydrophilic Interactions
Hydrophobic surfaces
Infection control
Internal Medicine
Laboratory Medicine
Metals
Metals - chemistry
Metals - pharmacology
Nosocomial infections
Pathology
Surface Properties
bactericidal activity
nanoparticles
aluminum
bacteriophages
healthcare-associated infections (HAI)
Online AccessGet full text

Cover

More Information
Summary:We studied antibacterial properties of organo-inorganic hybrid coatings on the AMg2 aluminum alloy including superhydrophilic and superhydrophobic nanotextured metal substrates with applied bacteriophage particles. Bactericidal activity of surfaces after artificial contamination with a bacterial suspension was evaluated. To increase bactericidal effect of the plates, bacteriophage was sorbed on their surface. In the experiments simulating possible spreading of HAI pathogens, higher bactericidal activity of superhydrophilic surfaces in comparison with superhydrophobic ones. Application of bacteriophage particles did not prevent primary colonization of textured metal surfaces by strains used in the experiment, but in some cases increases their bactericidal activity.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-019-04559-0