Iodide‐Mediated Rapid and Sensitive Surface Etching of Gold Nanostars for Biosensing

Iodide‐mediated surface etching can tailor the surface plasmon resonance of gold nanostars through etching of the high‐energy facets of the nanoparticle protrusions in a rapid and sensitive way. By exploring the underlying mechanisms of this etching and the key parameters influencing it (such as iod...

Full description

Saved in:
Bibliographic Details
Published inAngewandte Chemie International Edition Vol. 60; no. 18; pp. 9891 - 9896
Main Authors Xianyu, Yunlei, Lin, Yiyang, Chen, Qu, Belessiotis‐Richards, Alexis, Stevens, Molly M., Thomas, Michael R.
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 26.04.2021
John Wiley and Sons Inc
EditionInternational ed. in English
Subjects
Beads
Biosensors
Chemical synthesis
Communication
Communications
Etching
Gold
gold nanostars
Horseradish peroxidase
Immunoassays
iodide
Iodides
Nanoparticles
Oxidation
Peroxidase
plasmonic immunoassay
Resonance
surface etching
Surface plasmon resonance
gold nanostars
plasmonic immunoassay
iodide
surface etching
horseradish peroxidase
Online AccessGet full text

Cover

More Information
Summary:Iodide‐mediated surface etching can tailor the surface plasmon resonance of gold nanostars through etching of the high‐energy facets of the nanoparticle protrusions in a rapid and sensitive way. By exploring the underlying mechanisms of this etching and the key parameters influencing it (such as iodide, oxygen, pH, and temperature), we show its potential in a sensitive biosensing system. Horseradish peroxidase‐catalyzed oxidation of iodide enables control of the etching of gold nanostars to spherical gold nanoparticles, where the resulting spectral shift in the surface plasmon resonance yields a distinct color change of the solution. We further develop this enzyme‐modulated surface etching of gold nanostars into a versatile platform for plasmonic immunoassays, where a high sensitivity is possible by signal amplification via magnetic beads and click chemistry. We outline a rapid and sensitive nanoparticle etching‐based strategy for biosensing. Iodide modulates the plasmonic features of gold nanostars by etching them into spherical nanoparticles, being a versatile biosensing platform for enzyme detection and plasmonic immunoassays.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1433-7851
1521-3773
1521-3773
DOI:10.1002/anie.202017317