The Diagnosis and Treatment of Baroreflex Failure

Baroreflexes buffer changes in arterial pressure so that excessive fluctuations of blood pressure are avoided 1 – 7 . Baroreceptors in each carotid sinus send information about distention of the vessel wall by the glossopharyngeal nerves to the brain stem 8 . Other baroreceptors in the aortic arch a...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 329; no. 20; pp. 1449 - 1455
Main Authors Robertson, Rose Marie, Robertson, David, Hollister, Alan S, Biaggioni, Italo, Netterville, James L, Mosqueda-Garcia, Rogelio
Format Journal Article
LanguageEnglish
Published Boston, MA Massachusetts Medical Society 11.11.1993
Subjects
Adult
Baroreceptors
Baroreflex - physiology
Biological and medical sciences
Blood Pressure
Catecholamines - blood
Clonidine
Clonidine - therapeutic use
Cranial nerves. Spinal roots. Peripheral nerves. Autonomic nervous system. Gustation. Olfaction
Drug dosages
Epinephrine
Female
Headache
Heart
Heart rate
Humans
Hypersensitivity
Hypertension
Hypertension - diagnosis
Hypertension - drug therapy
Hypertension - physiopathology
Hypotension
Male
Medical diagnosis
Medical sciences
Middle Aged
Neck
Nerves
Nervous system (semeiology, syndromes)
Neurology
Norepinephrine
Nuclei
Paraganglioma
Patients
Pharynx
Plasma
Prospective Studies
Reflexes
Solitary tract nucleus
Surgery
Syndrome
Tachycardia - physiopathology
Tumors
Vasoactive agents
Human
Systolic pressure
Nervous system diseases
Cardiovascular disease
Catecholamine
Failures
Borderline hypertension
Heart rate
Treatment
Baroreflex
Diseases of the autonomic nervous system
Norepinephrine
Diagnosis
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Summary:Baroreflexes buffer changes in arterial pressure so that excessive fluctuations of blood pressure are avoided 1 – 7 . Baroreceptors in each carotid sinus send information about distention of the vessel wall by the glossopharyngeal nerves to the brain stem 8 . Other baroreceptors in the aortic arch and the great vessels of the thorax transmit similar information by the vagal nerves to the same brain-stem nuclei 9 . In addition, the blood volume in the thorax is sensed by low-pressure receptors linked by the vagal nerves to the brain stem. The brain-stem structures receiving this information are the commissural, dorsolateral, and medial portions . . .
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199311113292003