Blonanserin in the treatment of delirium

The purpose of the present study was to provide preliminary data on the usefulness and safety of blonanserin for patients with delirium in the intensive care unit (ICU). The charts of 32 consecutive patients with delirium in the ICU were retrospectively reviewed. These patients were treated with blo...

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Published inPsychiatry and clinical neurosciences Vol. 65; no. 4; pp. 389 - 391
Main Authors Kato, Koji, Yamada, Keigo, Maehara, Mizuki, Akama, Fumiaki, Kimoto, Keitaro, Saito, Mai, Yano, Hiroshi, Ichimura, Atsushi, Matsumoto, Hideo
Format Journal Article
LanguageEnglish
Published Melbourne, Australia Blackwell Publishing Asia 01.06.2011
Wiley-Blackwell
Subjects
Adult
Adult and adolescent clinical studies
Aged
Aged, 80 and over
Antipsychotic Agents - therapeutic use
atypical antipsychotics
Biological and medical sciences
blonanserin
Data processing
delirium
Delirium - drug therapy
Dopamine Antagonists - therapeutic use
Female
Humans
intensive care unit
Intensive care units
Male
Medical sciences
Middle Aged
Neuropharmacology
Organic mental disorders. Neuropsychology
Pharmacology. Drug treatments
Piperazines - therapeutic use
Piperidines - therapeutic use
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
Retrospective Studies
Serotonin Antagonists - therapeutic use
Side effects
treatment
Treatment Outcome
Delirium
Atypical antipsychotic
Treatment
Neuroleptic
Psychotropic
Blonanserin
atypical antipsychotics
Mental confusion
Intensive care unit
Organic mental disorder
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Abstract The purpose of the present study was to provide preliminary data on the usefulness and safety of blonanserin for patients with delirium in the intensive care unit (ICU). The charts of 32 consecutive patients with delirium in the ICU were retrospectively reviewed. These patients were treated with blonanserin. A total of 96.6% had reduction in Memorial Delirium Assessment Scale score. The proportion of patients with side‐effects was 24.1%. Blonanserin may be effective and safe in the treatment of delirium in the ICU.
AbstractList The purpose of the present study was to provide preliminary data on the usefulness and safety of blonanserin for patients with delirium in the intensive care unit (ICU). The charts of 32 consecutive patients with delirium in the ICU were retrospectively reviewed. These patients were treated with blonanserin. A total of 96.6% had reduction in Memorial Delirium Assessment Scale score. The proportion of patients with side‐effects was 24.1%. Blonanserin may be effective and safe in the treatment of delirium in the ICU.
Author Yamada, Keigo
Kato, Koji
Maehara, Mizuki
Yano, Hiroshi
Kimoto, Keitaro
Akama, Fumiaki
Saito, Mai
Matsumoto, Hideo
Ichimura, Atsushi
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  givenname: Mizuki
  surname: Maehara
  fullname: Maehara, Mizuki
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  givenname: Fumiaki
  surname: Akama
  fullname: Akama, Fumiaki
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  surname: Kimoto
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  surname: Yano
  fullname: Yano, Hiroshi
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Cites_doi 10.2165/11202620-000000000-00000
10.1016/S0033-3182(04)70170-X
10.1111/j.1440-1819.2010.02124.x
10.1176/appi.psy.43.3.175
10.1192/bjp.161.6.843
10.4088/JCP.v64n1106
10.1016/S0885-3924(96)00316-8
10.1007/s00134-003-2117-0
10.1186/cc6149
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Issue 4
Keywords Delirium
Atypical antipsychotic
Treatment
Neuroleptic
Psychotropic
Blonanserin
atypical antipsychotics
Mental confusion
Intensive care unit
Organic mental disorder
Language English
License CC BY 4.0
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SubjectTerms Adult
Adult and adolescent clinical studies
Aged
Aged, 80 and over
Antipsychotic Agents - therapeutic use
atypical antipsychotics
Biological and medical sciences
blonanserin
Data processing
delirium
Delirium - drug therapy
Dopamine Antagonists - therapeutic use
Female
Humans
intensive care unit
Intensive care units
Male
Medical sciences
Middle Aged
Neuropharmacology
Organic mental disorders. Neuropsychology
Pharmacology. Drug treatments
Piperazines - therapeutic use
Piperidines - therapeutic use
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
Retrospective Studies
Serotonin Antagonists - therapeutic use
Side effects
treatment
Treatment Outcome
Title Blonanserin in the treatment of delirium
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1440-1819.2011.02213.x
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