Long noncoding RNA SNHG17: a novel molecule in human cancers

Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several...

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Published inCancer cell international Vol. 22; no. 1; p. 104
Main Authors Ma, Li, Gao, Jin, Zhang, Niu, Wang, Jiawei, Xu, Tianwei, Lei, Tianyao, Zou, Xiaoteng, Wei, Chenchen, Wang, Zhaoxia
Format Journal Article
LanguageEnglish
Published England BioMed Central 05.03.2022
BMC
Subjects
Cancer
Diagnosis
Gene regulation
lncRNA
Prognosis
Review
SNHG17
Prognosis
lncRNA
Diagnosis
Gene regulation
Cancer
SNHG17
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Summary:Many studies in recent years have found that dysregulation of long non-coding RNAs (lncRNAs) can contribute to disease. Small nucleolar RNA host gene 17 (SNHG17) is a novel cancer-related lncRNA of the SNHG family which is highly expressed in various tumors and may exert oncogenic functions. Several studies have demonstrated that SNHG17 is closely related to the proliferation, migration, invasion, apoptosis, and chemical drug resistance of tumor cells, and clinical studies have found an association between high SNHG17 expression and poor prognosis. In this review, we summarize relevant studies investigating SNHG17, focusing on its biological function as well as its potential value for clinical applications.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
ISSN:1475-2867
1475-2867
DOI:10.1186/s12935-022-02529-7