Outcomes of office-based, open food challenges in the management of food allergy

• Published in: Journal of allergy and clinical immunology Vol. 128; no. 5; pp. 1120 - 1122
• Main Authors: Lieberman, Jay A., MD, Cox, Amanda L., MD, Vitale, Michelle, RN, Sampson, Hugh A., MD
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01.11.2011; Elsevier Limited
• Subjects: Adolescent; Allergies; Allergy and Immunology; Ambulatory Care; Child; Child, Preschool; Female; Food allergies; Food Hypersensitivity - diagnosis; Humans; Immunologic Tests - adverse effects; Infant; Male; Patients; Proteins; Retrospective Studies
• ISSN: 0091-6749; 1097-6825
• DOI: 10.1016/j.jaci.2011.07.012

Age (y) Food Clinical history SPT mean wheal diameter (mm) Food-specific sIgE (kUA/L) Reaction Dose causing reaction 9.2 Beef Urticaria 7 3.60 A, U, V 3 oz Hamburger(~20 g protein) 12.6 Egg Never ingested 4 2.28 C, W, U 1 g Protein 4.2 Egg Eczema flare 10 1.91 V, U 1/10 Egg(~0.75 g protein) 5.5 Peanut[low *] Never ingested 2 <0.35 V 2 Tablespoons peanut butter(~8 g protein) 5.75 Peanut Never ingested 0 3.71 C, W, D 1 Teaspoon peanut butter(~1.3 g protein) 4.8 Peanut Never ingested 5 <0.35 S, C, U 5 g Protein 5.1 Peanut No known reactions 4 1.65 S, C, U, V 5/8 Tablespoon peanut butter(~2.5 g protein) 14.9 Sesame No known reactions 6 16.2 U, V, W 2 Teaspoons tahini(~2 g protein) 1.2 Soy Never ingested 5 1.49 U, A 120 mL Soymilk(~4 g protein) 4.0 Walnut Never ingested 4 4.05 S, OP, U 5 g(~1.3 g protein) 6.4 Wheat Perioral rash ND[dagger] >100 OP, V, U ~1 g Protein 5.5 Wheat Urticaria (but mother reported recent tolerance to accidental ingestion) 0 10.3 U, C, W 1 Slice bread(~4 g protein) Table III Patients requiring epinephrine A, Angioedema; C, cough; D, dyspnea; OP, oropharyngeal itching/pain; S, sneeze; U, urticaria; V, vomiting; W, wheeze.