Diffuse MRI marrow pattern correlates with increased angiogenesis, advanced disease features and poor prognosis in newly diagnosed myeloma treated with novel agents

• Published in: Leukemia Vol. 24; no. 6; pp. 1206 - 1212
• Main Authors: Moulopoulos, L A, Dimopoulos, M A, Christoulas, D, Kastritis, E, Anagnostou, D, Koureas, A, Roussou, M, Gavriatopoulou, M, Migkou, M, Iakovaki, M, Gkotzamanidou, M, Tasidou, A, Terpos, E
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.06.2010; Nature Publishing Group
• Subjects: 631/67/2328; 692/699/67/1990/804; 692/700/1750; 692/700/565/1436; Aged; Angiogenesis; Antineoplastic Agents - therapeutic use; Biological and medical sciences; Biomarkers - analysis; Bone Diseases - pathology; Bone Marrow - blood supply; Bone Marrow - pathology; Bone Remodeling; Cancer Research; Care and treatment; Critical Care Medicine; Cytokines - metabolism; Diagnosis; Diffusion Magnetic Resonance Imaging; Female; Hematologic and hematopoietic diseases; Hematology; Humans; Immunodeficiencies. Immunoglobulinopathies; Immunoglobulinopathies; Immunopathology; Intensive; Internal Medicine; letter-to-the-editor; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Magnetic resonance imaging; Male; Medical sciences; Medicine; Medicine & Public Health; Multiple myeloma; Multiple Myeloma - blood supply; Multiple Myeloma - drug therapy; Multiple Myeloma - pathology; Myeloma; Neoplasm Staging; Neovascularization; Neovascularization, Pathologic - diagnosis; Oncology; Outcome and process assessment (Health Care); Patient outcomes; Prognosis; Survival Rate; Immunopathology; Prognosis; Hematology; Early stage; B cell neoplasm; Malignant hemopathy; Lymphoid neoplasm; Myeloma; Nuclear magnetic resonance imaging; Angiogenesis; Treatment; Immunoglobulinopathy; Lymphoproliferative syndrome; Bone marrow; Medical imagery; Advanced stage; Neovascularization; Cancer
• ISSN: 0887-6924; 1476-5551
• DOI: 10.1038/leu.2010.70