Simulated radioactive decontamination of biological samples using a portable DNA extraction instrument for rapid DNA profiling

Highlights • Removal of >99.996% of Co, Cs and Sr contaminants using the Maxwell® 16 System. • Residual dose rates corresponding to60 Co,137 Cs,90 Sr below the regulatory limits. • DNA yields similar to uncontaminated controls. • AmpF l STR® Identifiler® profiles derived in 26 min comparable to c...

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Bibliographic Details
Published inForensic science international Vol. 259; pp. 161 - 178
Main Authors Fregeau, Chantal J, Dalpe, Claude
Format Journal Article
LanguageEnglish
Published Ireland Elsevier Ireland Ltd 01.02.2016
Elsevier Limited
Subjects
Cesium Radioisotopes - analysis
Cobalt
Cobalt Radioisotopes - analysis
Contamination
Cotton
Decontamination
Decontamination - methods
Deoxyribonucleic acid
DNA
DNA Fingerprinting - methods
Dosage
Ethanol
Extraction
Forensic mobile laboratory
Forensic sciences
Genetic testing
Humans
Isotopes
Laboratories
Male
Pathology
Polyvinyl chloride
Portability
Radiological event
Rapid DNA process
Real-Time Polymerase Chain Reaction
Saliva
Salt
Strontium
Strontium Radioisotopes - analysis
Studies
Victim identification
Rapid DNA process
Decontamination
Victim identification
Forensic mobile laboratory
Radiological event
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Summary:Highlights • Removal of >99.996% of Co, Cs and Sr contaminants using the Maxwell® 16 System. • Residual dose rates corresponding to60 Co,137 Cs,90 Sr below the regulatory limits. • DNA yields similar to uncontaminated controls. • AmpF l STR® Identifiler® profiles derived in 26 min comparable to controls. • Contaminated samples processed safely in a forensic mobile laboratory.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2015.12.026