Effects of muscle strength and aerobic training on basal serum levels of IGF-1 and cortisol in elderly women

• Published in: Archives of gerontology and geriatrics Vol. 49; no. 3; pp. 343 - 347
• Main Authors: Vale, Rodrigo Gomes de Souza, de Oliveira, Rosana Dias, Pernambuco, Carlos Soares, de Meneses, Yúla Pires da Silveira Fontenele, Novaes, Jefferson da Silva, de Andrade, Armèle de Fátima Dornelas
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ireland Ltd 01.11.2009
• Subjects: Aerobic exercise; Aged; Analysis of Variance; Aquatic exercises; Body Mass Index; Cortisol; Cortisol levels during aging; Elderly women; Exercise - physiology; Female; Humans; Hydrocortisone - blood; IGF-1; Insulin-Like Growth Factor I - analysis; Internal Medicine; Muscle strength; Muscle Strength - physiology; Muscles; Serum; Aquatic exercises; IGF-1; Muscle strength; Cortisol levels during aging
• ISSN: 0167-4943; 1872-6976; 1872-6976
• DOI: 10.1016/j.archger.2008.11.011

The aim of this study was to compare the effects of muscle strength and aerobic training on the basal serum levels of IGF-1 and cortisol in elderly women. The subjects were divided in three groups as follows. 1. Strength training group (SG) submitted to the weight training called 1-repetition maximum test (1-RM, 75–85%). This group contained 12 subjects of mean age = 66.08 ± 3.37 years; and body mass index (BMI) = 26.0 ± 3.72 kg/m 2. (2) Aerobic training group (AG) submitted to aquatic exercise; they were 13 subjects of the mean age = 68.69 ± 4.70 years; and BMI = 29.19 ± 2.96 kg/m 2. (3) A control group (CG) of 10 subjects, of mean age = 68.80 ± 5.41 years; BMI = 29.70 ± 2.82 kg/m 2. The training periods were 12 weeks, Fasting blood was analyzed to measure IGF-1 and basal cortisol levels (by chemiluminescence method), both at the beginning and the end of the intervention. Student's t-test revealed increased IGF-1 in the SG ( p < 0.05) compared to the other two groups. Repeated-measure ANOVA showed also elevated IGF-1 ( p < 0.05) in the SG compared to the other groups (AG and CG). There were no differences in cortisol levels. In conclusion, high-intensity training caused changes in IGF-1. This suggests that strength training may provoke anabolic effects in elderly individuals.