Phosphorylation of the RNA Polymerase II Carboxyl-Terminal Domain by CDK9 Is Directly Responsible for Human Immunodeficiency Virus Type 1 Tat-Activated Transcriptional Elongation

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Published inMolecular and Cellular Biology Vol. 22; no. 13; pp. 4622 - 4637
Main Authors Kim, Young Kyeung, Bourgeois, Cyril F., Isel, Catherine, Churcher, Mark J., Karn, Jonathan
Format Journal Article
LanguageEnglish
Published United States American Society for Microbiology 01.07.2002
Taylor & Francis
Subjects
Base Sequence
Cdk9 protein
Chromosomal Proteins, Non-Histone
Cyclin-Dependent Kinase 9
Cyclin-Dependent Kinases - antagonists & inhibitors
Cyclin-Dependent Kinases - genetics
Cyclin-Dependent Kinases - metabolism
Dichlororibofuranosylbenzimidazole - pharmacology
Enzyme Inhibitors - pharmacology
Gene Products, tat - genetics
Gene Products, tat - metabolism
HeLa Cells
HIV-1 - genetics
HIV-1 - metabolism
Human immunodeficiency virus 1
Humans
Isopropyl Thiogalactoside - chemistry
Isopropyl Thiogalactoside - metabolism
Molecular Biology - methods
Molecular Sequence Data
Peptide Fragments - genetics
Peptide Fragments - metabolism
Phosphorylation
Repetitive Sequences, Amino Acid
RNA Polymerase II - genetics
RNA Polymerase II - metabolism
Saccharomyces cerevisiae Proteins - genetics
Saccharomyces cerevisiae Proteins - metabolism
Serine
tat Gene Products, Human Immunodeficiency Virus
Transcription Factors - genetics
Transcription Factors - metabolism
Transcription, Genetic
Transcriptional Elongation Factors
Transcriptional Regulation
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Summary:Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to MCB .asm.org, visit: MCB       
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Present address: Institut de Biologie Moléculaire et Cellulaire, UPR 9002 du CNRS, 67084 Strasbourg, France.
Corresponding author. Present address: Department of Molecular Biology and Microbiology, Case Western Reserve School of Medicine, W235 Wood Bldg., Cleveland, OH 44106. Phone: (216) 368-3420. Fax: (216) 368-3055. E-mail: jxk153@po.cwru.edu.
ISSN:0270-7306
1098-5549
1098-5549
DOI:10.1128/MCB.22.13.4622-4637.2002