Association of Intravenous Lipid Emulsion and Coagulase-Negative Staphylococcal Bacteremia in Neonatal Intensive Care Units

Coagulase-negative staphylococci have become the most common blood-culture isolates in neonatal intensive care units. 1 2 3 4 5 6 7 8 9 10 Many investigators have suggested that the use of intravascular catheters, particularly central venous catheters, is a major risk factor for staphylococcal bacte...

Full description

Saved in:
Bibliographic Details
Published inThe New England journal of medicine Vol. 323; no. 5; pp. 301 - 308
Main Authors Freeman, Jonathan, Goldmann, Donald A, Smith, Nancy E, Sidebottom, David G, Epstein, Michael F, Platt, Richard
Format Journal Article
LanguageEnglish
Published Boston, MA Massachusetts Medical Society 02.08.1990
Subjects
Bacteremia
Bacterial diseases
Biological and medical sciences
Birth weight
Catheterization, Central Venous - adverse effects
Catheters
Coagulase
Coagulase - analysis
Cross Infection - etiology
Data processing
Datasets
Disease control
Drug Contamination
Fat Emulsions, Intravenous - adverse effects
Female
Health risk assessment
Hospitalization
Hospitals
Humans
Infant, Newborn
Infants
Infections
Infectious diseases
Intensive care
Intensive care units
Intensive Care Units, Neonatal
Intravenous administration
Laboratories
Lipids
Malassezia furfur
Male
Medical sciences
Neonates
Newborn babies
Nosocomial infection
Nosocomial infections
Odds Ratio
Risk Factors
Sepsis - transmission
Staphylococcal Infections - transmission
Staphylococcus - enzymology
Staphylococcus epidermidis
Studies
Time Factors
Veterans
Womens health
Human
Infection
Emulsion
Newborn
Treatment
Intravenous administration
Pathophysiology
Bacteriosis
Lipids
Child
Bacteremia
Intensive care unit
Online AccessGet full text

Cover

More Information
Summary:Coagulase-negative staphylococci have become the most common blood-culture isolates in neonatal intensive care units. 1 2 3 4 5 6 7 8 9 10 Many investigators have suggested that the use of intravascular catheters, particularly central venous catheters, is a major risk factor for staphylococcal bacteremia in infants. 2 , 6 , 11 12 13 14 15 16 17 18 19 20 21 22 23 Intravascular catheters are used most often in very-low-birth-weight infants with long hospital stays, however, and two groups of investigators who adjusted for these potential confounding variables did not find that the catheters themselves were an independent cause of nosocomial coagulase-negative staphylococcal bacteremia. 3 , 7 Instead, they found that specific types of intravenous fluids were associated with this bacteremia. 3 , 7 In this study we determined the . . .
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199008023230504