How low can you go?

Extremely low numbers of active epidermal growth factor receptors are sufficient to drive tumor growth.

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Bibliographic Details
Published ineLife Vol. 7
Main Author Wiley, H Steven
Format Journal Article
LanguageEnglish
Published England eLife Sciences Publications Ltd 04.01.2018
eLife Sciences Publications, Ltd
Subjects
60 APPLIED LIFE SCIENCES
Cell adhesion & migration
Cell Biology
EGF receptor
EGFR
Endocytosis
Epidermal Growth Factor
Epidermal growth factor receptors
ErbB Receptors
Growth factor receptors
Humans
Hypotheses
Insight
Kinases
Laboratories
Ligands
Neoplasms
Phosphorylation
Receptors
Rodents
Systems Biology
Tumors
tumour
Ubiquitination
United States > US
mouse
cell biology
receptors
tumour
EGF receptor
endocytosis
human
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More Information
Summary:Extremely low numbers of active epidermal growth factor receptors are sufficient to drive tumor growth.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Commentary-3
content type line 23
PNNL-SA-131431
USDOE
AC05-76RL01830
ISSN:2050-084X
2050-084X
DOI:10.7554/elife.33604