An update on the arsenal: mining resistance genes for disease management of Brassica crops in the genomic era

• Published in: Horticulture research Vol. 7; no. 1; p. 34
• Main Authors: Lv, Honghao, Fang, Zhiyuan, Yang, Limei, Zhang, Yangyong, Wang, Yong
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 15.03.2020; Oxford University Press
• Subjects: 631/208/711; 631/449/2491; Agriculture; Biomedical and Life Sciences; Brassica; Cloning; Control methods; Crop production; Crops; Disease control; Disease resistance; Ecology; Economic importance; Environmental degradation; Fungal diseases; Gene mapping; Genes; Genetic resources; Genetics; Genomics; Health promotion; Life Sciences; Mapping; Molecular modelling; Nutrition; Plant Breeding/Biotechnology; Plant Genetics and Genomics; Plant Sciences; Review; Review Article; Plant breeding; Plant genetics
• ISSN: 2662-6810; 2052-7276
• DOI: 10.1038/s41438-020-0257-9

Brassica species include many economically important crops that provide nutrition and health-promoting substances to humans worldwide. However, as with all crops, their production is constantly threatened by emerging viral, bacterial, and fungal diseases, whose incidence has increased in recent years. Traditional methods of control are often costly, present limited effectiveness, and cause environmental damage; instead, the ideal approach is to mine and utilize the resistance genes of the Brassica crop hosts themselves. Fortunately, the development of genomics, molecular genetics, and biological techniques enables us to rapidly discover and apply resistance (R) genes. Herein, the R genes identified in Brassica crops are summarized, including their mapping and cloning, possible molecular mechanisms, and application in resistance breeding. Future perspectives concerning how to accurately discover additional R gene resources and efficiently utilize these genes in the genomic era are also discussed.