Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population

Qing Wang and colleagues report a genome-wide association study for coronary artery disease (CAD) in a Chinese Han population. They identify a locus on chromosome 6p24.1 newly associated with CAD. Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide...

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Published inNature genetics Vol. 43; no. 4; pp. 345 - 349
Main Authors Wang, Fan, Xu, Cheng-Qi, He, Qing, Cai, Jian-Ping, Li, Xiu-Chun, Wang, Dan, Xiong, Xin, Liao, Yu-Hua, Zeng, Qiu-Tang, Yang, Yan-Zong, Cheng, Xiang, Li, Cong, Yang, Rong, Wang, Chu-Chu, Wu, Gang, Lu, Qiu-Lun, Bai, Ying, Huang, Yu-Feng, Yin, Dan, Yang, Qing, Wang, Xiao-Jing, Dai, Da-Peng, Zhang, Rong-Feng, Wan, Jing, Ren, Jiang-Hua, Li, Si-Si, Zhao, Yuan-Yuan, Fu, Fen-Fen, Huang, Yuan, Li, Qing-Xian, Shi, Sheng-Wei, Lin, Nan, Pan, Zhen-Wei, Li, Yue, Yu, Bo, Wu, Yan-Xia, Ke, Yu-He, Lei, Jian, Wang, Nan, Luo, Chun-Yan, Ji, Li-Ying, Gao, Lian-Jun, Li, Lei, Liu, Hui, Huang, Er-Wen, Cui, Jin, Jia, Na, Ren, Xiang, Li, Hui, Ke, Tie, Zhang, Xian-Qin, Liu, Jing-Yu, Liu, Mu-Gen, Xia, Hao, Yang, Bo, Shi, Li-Song, Xia, Yun-Long, Tu, Xin, Wang, Qing K
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.04.2011
Nature Publishing Group
Subjects
631/208/205/2138
631/208/727/2000
692/699/75/593/15
692/700/478/174
Agriculture
Alleles
Animal Genetics and Genomics
Asian Continental Ancestry Group - genetics
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cancer Research
Case-Control Studies
China
Chromosomes, Human, Pair 6 - genetics
Coronary Artery Disease - genetics
Coronary heart disease
Disease susceptibility
Female
Fundamental and applied biological sciences. Psychology
Gene Function
Genetic aspects
Genetic Predisposition to Disease
Genetics of eukaryotes. Biological and molecular evolution
Genome-Wide Association Study
Genomes
Heart attacks
Human
Human Genetics
Humans
Hypertension
letter
Linkage Disequilibrium
Male
Polymorphism, Single Nucleotide
Population genetics, reproduction patterns
Regression analysis
Risk Factors
RNA, Messenger - genetics
Single nucleotide polymorphisms
Asia
China
Far east
Vascular disease
Human
Cardiovascular disease
Population genetics
Ethnic group
Atherosclerosis
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Abstract Qing Wang and colleagues report a genome-wide association study for coronary artery disease (CAD) in a Chinese Han population. They identify a locus on chromosome 6p24.1 newly associated with CAD. Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD ( P = 5.00 × 10 −3 , stage 2 validation; P = 3.00 × 10 −3 , P = 1.19 × 10 −8 and P = 4.00 × 10 −3 in three independent stage 3 replication populations; P = 4.87 × 10 −12 , odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population.
AbstractList Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD (P = 5.00 x [10.sup.-3], stage 2 validation; P = 3.00 x [10.sup.-3], P = 1.19 x [10.sup.-8] and P = 4.00 x [10.sup.-3] in three independent stage 3 replication populations; P = 4.87 x [10.sup.-12], odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population.
Qing Wang and colleagues report a genome-wide association study for coronary artery disease (CAD) in a Chinese Han population. They identify a locus on chromosome 6p24.1 newly associated with CAD. Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD ( P = 5.00 × 10 −3 , stage 2 validation; P = 3.00 × 10 −3 , P = 1.19 × 10 −8 and P = 4.00 × 10 −3 in three independent stage 3 replication populations; P = 4.87 × 10 −12 , odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population.
Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD (P = 5.00 × 10^sup -3^, stage 2 validation; P = 3.00 × 10^sup -3^, P = 1.19 × 10^sup -8^ and P = 4.00 × 10^sup -3^ in three independent stage 3 replication populations; P = 4.87 × 10^sup -12^, odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population. [PUBLICATION ABSTRACT]
Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population. We identified a new association between rs6903956 in a putative gene denoted as C6orf105 on chromosome 6p24.1 and CAD (P = 5.00 × 10⁻³, stage 2 validation; P = 3.00 × 10⁻³, P = 1.19 × 10⁻⁸ and P = 4.00 × 10⁻³ in three independent stage 3 replication populations; P = 4.87 × 10⁻¹², odds ratio = 1.51 in the combined population). The minor risk allele A of rs6903956 is associated with decreased C6orf105 mRNA expression. We report the first GWAS for CAD in the Chinese Han population and identify a SNP, rs6903956, in C6orf105 associated with susceptibility to CAD in this population.
Audience Academic
Author Wang, Nan
Wang, Dan
Ke, Tie
Ke, Yu-He
Jia, Na
Cui, Jin
Li, Xiu-Chun
Yin, Dan
Liu, Hui
Wu, Gang
Huang, Yuan
Luo, Chun-Yan
Huang, Er-Wen
Liu, Jing-Yu
Bai, Ying
Lei, Jian
Liu, Mu-Gen
Tu, Xin
Ren, Xiang
Liao, Yu-Hua
Li, Cong
Xia, Yun-Long
Xiong, Xin
Yang, Yan-Zong
Lu, Qiu-Lun
Yang, Rong
Cai, Jian-Ping
Ren, Jiang-Hua
Yang, Bo
Li, Yue
Zhang, Rong-Feng
Wang, Qing K
Li, Qing-Xian
Xia, Hao
Cheng, Xiang
Xu, Cheng-Qi
Wang, Chu-Chu
Lin, Nan
Zhang, Xian-Qin
Wu, Yan-Xia
Shi, Sheng-Wei
Yang, Qing
Li, Si-Si
Gao, Lian-Jun
Ji, Li-Ying
Zeng, Qiu-Tang
Li, Hui
He, Qing
Wang, Xiao-Jing
Wan, Jing
Shi, Li-Song
Zhao, Yuan-Yuan
Huang, Yu-Feng
Dai, Da-Peng
Pan, Zhen-Wei
Yu, Bo
Wang, Fan
Fu, Fen-Fen
Li, Lei
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Cites_doi 10.1038/nrg1521
10.1038/ng827
10.1056/NEJM199404143301503
10.1038/ng.323
10.1056/NEJMoa072366
10.1086/521581
10.1016/j.cell.2008.10.022
10.1038/ng.72
10.1161/ATVBAHA.107.157248
10.1161/CIRCULATIONAHA.107.730614
10.1001/jama.290.7.898
10.1038/ng.76
10.1038/ng.314
10.1210/er.2001-0025
10.1097/01.hco.0000160373.77190.f1
10.1016/S0140-6736(06)68770-9
10.1093/hmg/ddn132
10.1161/01.CIR.103.10.1382
10.1126/science.1142447
10.1373/clinchem.2008.112797
10.1161/ATVBAHA.108.176065
10.1161/01.CIR.97.18.1837
10.1093/ajh/7.7.7S
10.1161/01.CIR.0000133440.86427.26
10.1161/01.ATV.0000075081.51227.86
10.1038/nature05911
10.1016/S1016-8478(23)17000-2
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References Lopez, Mathers, Ezzati, Jamison, Murray (CR1) 2006; 367
Wu, von Eckardstein (CR25) 2003; 24
Broeckel (CR4) 2002; 30
Bustin (CR28) 2009; 55
Shen (CR26) 2007; 81
Assimes (CR21) 2008; 17
CR16
Hirschhorn, Daly (CR10) 2005; 6
CR14
Trégouët (CR15) 2009; 41
McPherson (CR11) 2007; 316
Wilson (CR9) 1994; 7
Wilson (CR5) 1998; 97
Helgadottir (CR17) 2008; 40
Gudbjartsson (CR18) 2009; 41
Wang (CR3) 2005; 20
Hanke, Lenz, Hess, Spindler, Weidemann (CR24) 2001; 103
Samani (CR12) 2007; 357
Willer (CR13) 2008; 40
Shen (CR19) 2008; 28
Gibbons (CR7) 2004; 109
Zhou (CR22) 2008; 28
Seo, Kim, Kim (CR23) 2001; 11
Zhang (CR27) 2008; 135
Schunkert (CR20) 2008; 117
Sing, Stengard, Kardia (CR2) 2003; 23
Khot (CR6) 2003; 290
Marenberg, Risch, Berkman, Floderus, de Faire (CR8) 1994; 330
18048766 - Arterioscler Thromb Vasc Biol. 2008 Feb;28(2):360-5
18443000 - Hum Mol Genet. 2008 Aug 1;17(15):2320-8
19198609 - Nat Genet. 2009 Mar;41(3):334-41
19198610 - Nat Genet. 2009 Mar;41(3):342-7
9603539 - Circulation. 1998 May 12;97(18):1837-47
12730090 - Arterioscler Thromb Vasc Biol. 2003 Jul 1;23(7):1190-6
17554300 - Nature. 2007 Jun 7;447(7145):661-78
8127331 - N Engl J Med. 1994 Apr 14;330(15):1041-6
19246619 - Clin Chem. 2009 Apr;55(4):611-22
15716906 - Nat Rev Genet. 2005 Feb;6(2):95-108
17634449 - N Engl J Med. 2007 Aug 2;357(5):443-53
11818963 - Nat Genet. 2002 Feb;30(2):210-4
19070573 - Cell. 2008 Dec 12;135(6):1017-27
17478681 - Science. 2007 Jun 8;316(5830):1488-91
12928466 - JAMA. 2003 Aug 20;290(7):898-904
18362232 - Circulation. 2008 Apr 1;117(13):1675-84
15226250 - Circulation. 2004 Jun 29;109(25 Suppl 1):IV47-58
7946184 - Am J Hypertens. 1994 Jul;7(7 Pt 2):7S-12S
12700179 - Endocr Rev. 2003 Apr;24(2):183-217
17847002 - Am J Hum Genet. 2007 Oct;81(4):780-91
18176561 - Nat Genet. 2008 Feb;40(2):217-24
15861005 - Curr Opin Cardiol. 2005 May;20(3):182-8
11245640 - Circulation. 2001 Mar 13;103(10):1382-5
18193043 - Nat Genet. 2008 Feb;40(2):161-9
18757290 - Arterioscler Thromb Vasc Biol. 2008 Nov;28(11):2085-9
11266118 - Mol Cells. 2001 Feb 28;11(1):35-40
19198611 - Nat Genet. 2009 Mar;41(3):283-5
16731270 - Lancet. 2006 May 27;367(9524):1747-57
NJ Samani (BFng783_CR12) 2007; 357
Q Wang (BFng783_CR3) 2005; 20
FC Wu (BFng783_CR25) 2003; 24
GH Gibbons (BFng783_CR7) 2004; 109
AD Lopez (BFng783_CR1) 2006; 367
P Wilson (BFng783_CR9) 1994; 7
CJ Willer (BFng783_CR13) 2008; 40
H Hanke (BFng783_CR24) 2001; 103
A Helgadottir (BFng783_CR17) 2008; 40
UN Khot (BFng783_CR6) 2003; 290
JN Hirschhorn (BFng783_CR10) 2005; 6
ME Marenberg (BFng783_CR8) 1994; 330
PW Wilson (BFng783_CR5) 1998; 97
X Zhang (BFng783_CR27) 2008; 135
TL Assimes (BFng783_CR21) 2008; 17
L Zhou (BFng783_CR22) 2008; 28
J Seo (BFng783_CR23) 2001; 11
DF Gudbjartsson (BFng783_CR18) 2009; 41
SA Bustin (BFng783_CR28) 2009; 55
BFng783_CR16
DA Trégouët (BFng783_CR15) 2009; 41
GQ Shen (BFng783_CR19) 2008; 28
BFng783_CR14
GQ Shen (BFng783_CR26) 2007; 81
CF Sing (BFng783_CR2) 2003; 23
R McPherson (BFng783_CR11) 2007; 316
H Schunkert (BFng783_CR20) 2008; 117
U Broeckel (BFng783_CR4) 2002; 30
References_xml – volume: 6
  start-page: 95
  year: 2005
  end-page: 108
  ident: CR10
  article-title: Genome-wide association studies for common diseases and complex traits
  publication-title: Nat. Rev. Genet.
  doi: 10.1038/nrg1521
  contributor:
    fullname: Daly
– volume: 30
  start-page: 210
  year: 2002
  end-page: 214
  ident: CR4
  article-title: A comprehensive linkage analysis for myocardial infarction and its related risk factors
  publication-title: Nat. Genet.
  doi: 10.1038/ng827
  contributor:
    fullname: Broeckel
– volume: 330
  start-page: 1041
  year: 1994
  end-page: 1046
  ident: CR8
  article-title: Genetic susceptibility to death from coronary heart disease in a study of twins
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM199404143301503
  contributor:
    fullname: de Faire
– ident: CR14
– ident: CR16
– volume: 41
  start-page: 342
  year: 2009
  end-page: 347
  ident: CR18
  article-title: Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
  publication-title: Nat. Genet.
  doi: 10.1038/ng.323
  contributor:
    fullname: Gudbjartsson
– volume: 357
  start-page: 443
  year: 2007
  ident: CR12
  article-title: Genomewide association analysis of coronary artery disease
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa072366
  contributor:
    fullname: Samani
– volume: 81
  start-page: 780
  year: 2007
  end-page: 791
  ident: CR26
  article-title: An variant is associated with familial and premature coronary artery disease and myocardial infarction
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/521581
  contributor:
    fullname: Shen
– volume: 135
  start-page: 1017
  year: 2008
  end-page: 1027
  ident: CR27
  article-title: Mutation in nuclear pore component leads to atrial fibrillation and early sudden cardiac death
  publication-title: Cell
  doi: 10.1016/j.cell.2008.10.022
  contributor:
    fullname: Zhang
– volume: 40
  start-page: 217
  year: 2008
  end-page: 224
  ident: CR17
  article-title: The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
  publication-title: Nat. Genet.
  doi: 10.1038/ng.72
  contributor:
    fullname: Helgadottir
– volume: 28
  start-page: 360
  year: 2008
  end-page: 365
  ident: CR19
  article-title: Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/ATVBAHA.107.157248
  contributor:
    fullname: Shen
– volume: 117
  start-page: 1675
  year: 2008
  end-page: 1684
  ident: CR20
  article-title: Repeated replication and a prospective meta-analysis of the association between chromosome 9p21. 3 and coronary artery disease
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.107.730614
  contributor:
    fullname: Schunkert
– volume: 290
  start-page: 898
  year: 2003
  end-page: 904
  ident: CR6
  article-title: Prevalence of conventional risk factors in patients with coronary heart disease
  publication-title: J. Am. Med. Assoc.
  doi: 10.1001/jama.290.7.898
  contributor:
    fullname: Khot
– volume: 40
  start-page: 161
  year: 2008
  end-page: 169
  ident: CR13
  article-title: Newly identified loci that influence lipid concentrations and risk of coronary artery disease
  publication-title: Nat. Genet.
  doi: 10.1038/ng.76
  contributor:
    fullname: Willer
– volume: 11
  start-page: 35
  year: 2001
  end-page: 40
  ident: CR23
  article-title: Cloning of androgen-inducible gene 1 ( ) from human dermal papilla cells
  publication-title: Mol. Cells
  contributor:
    fullname: Kim
– volume: 41
  start-page: 283
  year: 2009
  end-page: 285
  ident: CR15
  article-title: Genome-wide haplotype association study identifies the - - gene cluster as a risk locus for coronary artery disease
  publication-title: Nat. Genet.
  doi: 10.1038/ng.314
  contributor:
    fullname: Trégouët
– volume: 24
  start-page: 183
  year: 2003
  end-page: 217
  ident: CR25
  article-title: Androgens and coronary artery disease
  publication-title: Endocr. Rev.
  doi: 10.1210/er.2001-0025
  contributor:
    fullname: von Eckardstein
– volume: 20
  start-page: 182
  year: 2005
  end-page: 188
  ident: CR3
  article-title: Molecular genetics of coronary artery disease
  publication-title: Curr. Opin. Cardiol.
  doi: 10.1097/01.hco.0000160373.77190.f1
  contributor:
    fullname: Wang
– volume: 367
  start-page: 1747
  year: 2006
  end-page: 1757
  ident: CR1
  article-title: Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data
  publication-title: Lancet
  doi: 10.1016/S0140-6736(06)68770-9
  contributor:
    fullname: Murray
– volume: 17
  start-page: 2320
  year: 2008
  end-page: 2328
  ident: CR21
  article-title: Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/ddn132
  contributor:
    fullname: Assimes
– volume: 103
  start-page: 1382
  year: 2001
  end-page: 1385
  ident: CR24
  article-title: Effect of testosterone on plaque development and androgen receptor expression in the arterial vessel wall
  publication-title: Circulation
  doi: 10.1161/01.CIR.103.10.1382
  contributor:
    fullname: Weidemann
– volume: 316
  start-page: 1488
  year: 2007
  ident: CR11
  article-title: A common allele on chromosome 9 associated with coronary heart disease
  publication-title: Science
  doi: 10.1126/science.1142447
  contributor:
    fullname: McPherson
– volume: 55
  start-page: 611
  year: 2009
  end-page: 622
  ident: CR28
  article-title: The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
  publication-title: Clin. Chem.
  doi: 10.1373/clinchem.2008.112797
  contributor:
    fullname: Bustin
– volume: 28
  start-page: 2085
  year: 2008
  end-page: 2089
  ident: CR22
  article-title: Associations between single nucleotide polymorphisms on chromosome 9p21 and risk of coronary heart disease in Chinese Han population
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/ATVBAHA.108.176065
  contributor:
    fullname: Zhou
– volume: 97
  start-page: 1837
  year: 1998
  end-page: 1847
  ident: CR5
  article-title: Prediction of coronary heart disease using risk factor categories
  publication-title: Circulation
  doi: 10.1161/01.CIR.97.18.1837
  contributor:
    fullname: Wilson
– volume: 7
  start-page: 7S
  year: 1994
  end-page: 12S
  ident: CR9
  article-title: Established risk factors and coronary artery disease: the Framingham Study
  publication-title: Am. J. Hypertens.
  doi: 10.1093/ajh/7.7.7S
  contributor:
    fullname: Wilson
– volume: 109
  start-page: IV47
  year: 2004
  end-page: IV58
  ident: CR7
  article-title: Genetic markers: progress and potential for cardiovascular disease
  publication-title: Circulation
  doi: 10.1161/01.CIR.0000133440.86427.26
  contributor:
    fullname: Gibbons
– volume: 23
  start-page: 1190
  year: 2003
  end-page: 1196
  ident: CR2
  article-title: Genes, environment, and cardiovascular disease
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/01.ATV.0000075081.51227.86
  contributor:
    fullname: Kardia
– volume: 97
  start-page: 1837
  year: 1998
  ident: BFng783_CR5
  publication-title: Circulation
  doi: 10.1161/01.CIR.97.18.1837
  contributor:
    fullname: PW Wilson
– volume: 28
  start-page: 2085
  year: 2008
  ident: BFng783_CR22
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/ATVBAHA.108.176065
  contributor:
    fullname: L Zhou
– volume: 117
  start-page: 1675
  year: 2008
  ident: BFng783_CR20
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.107.730614
  contributor:
    fullname: H Schunkert
– volume: 23
  start-page: 1190
  year: 2003
  ident: BFng783_CR2
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/01.ATV.0000075081.51227.86
  contributor:
    fullname: CF Sing
– volume: 28
  start-page: 360
  year: 2008
  ident: BFng783_CR19
  publication-title: Arterioscler. Thromb. Vasc. Biol.
  doi: 10.1161/ATVBAHA.107.157248
  contributor:
    fullname: GQ Shen
– volume: 81
  start-page: 780
  year: 2007
  ident: BFng783_CR26
  publication-title: Am. J. Hum. Genet.
  doi: 10.1086/521581
  contributor:
    fullname: GQ Shen
– volume: 330
  start-page: 1041
  year: 1994
  ident: BFng783_CR8
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJM199404143301503
  contributor:
    fullname: ME Marenberg
– volume: 7
  start-page: 7S
  year: 1994
  ident: BFng783_CR9
  publication-title: Am. J. Hypertens.
  doi: 10.1093/ajh/7.7.7S
  contributor:
    fullname: P Wilson
– volume: 316
  start-page: 1488
  year: 2007
  ident: BFng783_CR11
  publication-title: Science
  doi: 10.1126/science.1142447
  contributor:
    fullname: R McPherson
– ident: BFng783_CR14
  doi: 10.1038/nature05911
– volume: 135
  start-page: 1017
  year: 2008
  ident: BFng783_CR27
  publication-title: Cell
  doi: 10.1016/j.cell.2008.10.022
  contributor:
    fullname: X Zhang
– volume: 367
  start-page: 1747
  year: 2006
  ident: BFng783_CR1
  publication-title: Lancet
  doi: 10.1016/S0140-6736(06)68770-9
  contributor:
    fullname: AD Lopez
– volume: 6
  start-page: 95
  year: 2005
  ident: BFng783_CR10
  publication-title: Nat. Rev. Genet.
  doi: 10.1038/nrg1521
  contributor:
    fullname: JN Hirschhorn
– volume: 30
  start-page: 210
  year: 2002
  ident: BFng783_CR4
  publication-title: Nat. Genet.
  doi: 10.1038/ng827
  contributor:
    fullname: U Broeckel
– volume: 41
  start-page: 283
  year: 2009
  ident: BFng783_CR15
  publication-title: Nat. Genet.
  doi: 10.1038/ng.314
  contributor:
    fullname: DA Trégouët
– volume: 40
  start-page: 217
  year: 2008
  ident: BFng783_CR17
  publication-title: Nat. Genet.
  doi: 10.1038/ng.72
  contributor:
    fullname: A Helgadottir
– volume: 357
  start-page: 443
  year: 2007
  ident: BFng783_CR12
  publication-title: N. Engl. J. Med.
  doi: 10.1056/NEJMoa072366
  contributor:
    fullname: NJ Samani
– volume: 17
  start-page: 2320
  year: 2008
  ident: BFng783_CR21
  publication-title: Hum. Mol. Genet.
  doi: 10.1093/hmg/ddn132
  contributor:
    fullname: TL Assimes
– volume: 55
  start-page: 611
  year: 2009
  ident: BFng783_CR28
  publication-title: Clin. Chem.
  doi: 10.1373/clinchem.2008.112797
  contributor:
    fullname: SA Bustin
– ident: BFng783_CR16
– volume: 290
  start-page: 898
  year: 2003
  ident: BFng783_CR6
  publication-title: J. Am. Med. Assoc.
  doi: 10.1001/jama.290.7.898
  contributor:
    fullname: UN Khot
– volume: 20
  start-page: 182
  year: 2005
  ident: BFng783_CR3
  publication-title: Curr. Opin. Cardiol.
  doi: 10.1097/01.hco.0000160373.77190.f1
  contributor:
    fullname: Q Wang
– volume: 109
  start-page: IV47
  year: 2004
  ident: BFng783_CR7
  publication-title: Circulation
  doi: 10.1161/01.CIR.0000133440.86427.26
  contributor:
    fullname: GH Gibbons
– volume: 11
  start-page: 35
  year: 2001
  ident: BFng783_CR23
  publication-title: Mol. Cells
  doi: 10.1016/S1016-8478(23)17000-2
  contributor:
    fullname: J Seo
– volume: 41
  start-page: 342
  year: 2009
  ident: BFng783_CR18
  publication-title: Nat. Genet.
  doi: 10.1038/ng.323
  contributor:
    fullname: DF Gudbjartsson
– volume: 103
  start-page: 1382
  year: 2001
  ident: BFng783_CR24
  publication-title: Circulation
  doi: 10.1161/01.CIR.103.10.1382
  contributor:
    fullname: H Hanke
– volume: 24
  start-page: 183
  year: 2003
  ident: BFng783_CR25
  publication-title: Endocr. Rev.
  doi: 10.1210/er.2001-0025
  contributor:
    fullname: FC Wu
– volume: 40
  start-page: 161
  year: 2008
  ident: BFng783_CR13
  publication-title: Nat. Genet.
  doi: 10.1038/ng.76
  contributor:
    fullname: CJ Willer
SSID ssj0014408
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Snippet Qing Wang and colleagues report a genome-wide association study for coronary artery disease (CAD) in a Chinese Han population. They identify a locus on...
Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European...
SourceID proquest
gale
crossref
pubmed
pascalfrancis
springer
SourceType Aggregation Database
Index Database
Publisher
StartPage 345
SubjectTerms 631/208/205/2138
631/208/727/2000
692/699/75/593/15
692/700/478/174
Agriculture
Alleles
Animal Genetics and Genomics
Asian Continental Ancestry Group - genetics
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cancer Research
Case-Control Studies
China
Chromosomes, Human, Pair 6 - genetics
Coronary Artery Disease - genetics
Coronary heart disease
Disease susceptibility
Female
Fundamental and applied biological sciences. Psychology
Gene Function
Genetic aspects
Genetic Predisposition to Disease
Genetics of eukaryotes. Biological and molecular evolution
Genome-Wide Association Study
Genomes
Heart attacks
Human
Human Genetics
Humans
Hypertension
letter
Linkage Disequilibrium
Male
Polymorphism, Single Nucleotide
Population genetics, reproduction patterns
Regression analysis
Risk Factors
RNA, Messenger - genetics
Single nucleotide polymorphisms
Title Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population
URI https://link.springer.com/article/10.1038/ng.783
https://www.ncbi.nlm.nih.gov/pubmed/21378986
https://www.proquest.com/docview/861329088
https://search.proquest.com/docview/859313856
Volume 43
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