An overview of targets and therapies for glioblastoma multiforme

Glioblastoma multiforme (GBM) affects individuals above 65 years of age and has low median survival rate. Due to limited treatment options, lack of effective diagnosis, and palliative care, there is an urgent need to develop new therapeutic strategies to combat GBM. This review provides an overview...

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Bibliographic Details
Published inJournal of cancer research and therapeutics Vol. 18; no. 3; pp. 591 - 598
Main Authors Chandrasekar, Gayathri, Bansal, Vinay, Panigrahi, Manas, Kitambi, Satish
Format Journal Article
LanguageEnglish
Published Mumbai Wolters Kluwer India Pvt. Ltd 01.07.2022
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Subjects
Brain cancer
Cancer
Cancer therapies
Care and treatment
Development and progression
Diagnosis
Drug targeting
Glioblastoma multiforme
Glioma
Medicin och hälsovetenskap
Oncology, Experimental
Targeted cancer therapy
Tumors
India
treatment
glioma
glioblastoma
Cancer
care
drug
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Summary:Glioblastoma multiforme (GBM) affects individuals above 65 years of age and has low median survival rate. Due to limited treatment options, lack of effective diagnosis, and palliative care, there is an urgent need to develop new therapeutic strategies to combat GBM. This review provides an overview of the current clinical trial scenario with a special focus on new targets, repurposed drugs, and technologies in the field of GBM. The use of technological advances and artificial intelligence in diagnosis and imaging is also discussed. In addition, this review also highlights the need to design a dynamic palliative care strategy for end-of-life management of patients with GBM.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0973-1482
1998-4138
1998-4138
DOI:10.4103/jcrt.jcrt_1324_21