Aging and limb alter the neuromuscular control of goal-directed movements

• Published in: Experimental brain research Vol. 232; no. 6; pp. 1759 - 1771
• Main Authors: Kwon, MinHyuk, Chen, Yen-Ting, Fox, Emily J., Christou, Evangelos A.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2014; Springer; Springer Nature B.V
• Subjects: Accuracy; Activities of daily living; Adult; Aged; Aging; Aging - physiology; Ankle; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Case-Control Studies; Elbow; Electromyography; Extremities (Anatomy); Extremities - physiology; Female; Fundamental and applied biological sciences. Psychology; Goals; Humans; Male; Movement - physiology; Muscle Contraction - physiology; Muscle function; Muscle, Skeletal - physiology; Neurology; Neuromuscular Junction - physiology; Neurosciences; Older people; Physiological aspects; Psychological aspects; Research Article; Vertebrates: nervous system and sense organs; Young Adult; Young adults; United States; United States > US; Aging; Limbs; Goal-directed movement; EMG; Senescence; Electrophysiology; Electromyography
• ISSN: 0014-4819; 1432-1106
• DOI: 10.1007/s00221-014-3868-2

The purpose of this study was to determine whether the neuromuscular control of goal-directed movements is different for young and older adults with the upper and lower limbs. Twenty young (25.1 ± 3.9 years) and twenty older adults (71.5 ± 4.8 years) attempted to accurately match the displacement of their limb to a spatiotemporal target during ankle dorsiflexion or elbow flexion movements. We quantified neuromuscular control by examining the movement endpoint accuracy and variability, and the antagonistic muscle activity using surface electromyography (EMG). Our results indicate that older adults exhibit impaired endpoint accuracy with both limbs due to greater time variability. In addition, older adults exhibit greater EMG burst and lower EMG burst variability as well as lower coactivation of the antagonistic muscles. The impaired accuracy of older adults during upper limb movements was related to lower coactivation of the antagonistic muscles, whereas their impaired accuracy during lower limb movements was related to the amplified EMG bursts. The upper limb exhibited greater movement control than the lower limb, and different neuromuscular parameters were related to the accuracy and consistency for each limb. Greater endpoint error during upper limb movements was related to lower coactivation of the antagonistic muscles, whereas greater endpoint error during lower limb movements was related to the amplified EMG bursts. These findings indicate that the age-associated impairments in movement control are associated with altered activation of the involved antagonistic muscles. In addition, independent of age, the neuromuscular control of goal-directed movements is different for the upper and lower limbs.