Interference of B lymphocyte tolerance by prolactin in rheumatic autoimmune diseases

Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) are the most common rheumatic autoimmune diseases/disorders (RADs) that affect autologous connective tissues as a result of the breakdown of the self-tolerance mechanisms of the immune system. Prolactin, a gl...

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Published inHeliyon Vol. 9; no. 6; p. e16977
Main Authors Mousavi, Mohammad Javad, Alizadeh, Ardalan, Ghotloo, Somayeh
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.06.2023
Elsevier
Subjects
animals
antibodies
apoptosis
Autoimmune disease
B lymphocyte
B lymphocyte tolerance
B-lymphocytes
cytokines
glycoproteins
lupus erythematosus
lymphocyte proliferation
pathogenesis
Prolactin
Review
Rheumatic autoimmune disease
rheumatoid arthritis
sclerosis
Tolerance
B lymphocyte tolerance
B lymphocyte
Tolerance
Autoimmune disease
Rheumatic autoimmune disease
Prolactin
Online AccessGet full text
ISSN2405-8440
2405-8440
DOI10.1016/j.heliyon.2023.e16977

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Abstract Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) are the most common rheumatic autoimmune diseases/disorders (RADs) that affect autologous connective tissues as a result of the breakdown of the self-tolerance mechanisms of the immune system. Prolactin, a glycoprotein hormone, has been known for its crucial role in the pathogenesis of these rheumatic autoimmune diseases. In addition to regulating lymphocyte proliferation and antibody synthesis, prolactin is also responsible for regulating cytokine production. Moreover, it contributes to the breakdown of central and peripheral tolerance mechanisms of B lymphocytes. Given the crucial role of prolactin in the pathogenesis of the mentioned RADs, prolactin may contribute to their pathogenesis by the breakdown of tolerance. In the present study, the key role of prolactin to the breakdown of B lymphocyte tolerance and its possible implication for the pathogenesis of these diseases is discussed. Current literature supports prolactin's role in the breakdown of B lymphocyte central and peripheral tolerance mechanisms, such apoptosis, receptor editing, and also anergy. Therefore, prolactin may contribute to the pathogenesis of RADs by the breakdown of B lymphocyte tolerance. However, more investigations, particularly in RA and SSc animal models, are required to precisely address the pathologic role of prolactin.
AbstractList Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) are the most common rheumatic autoimmune diseases/disorders (RADs) that affect autologous connective tissues as a result of the breakdown of the self-tolerance mechanisms of the immune system. Prolactin, a glycoprotein hormone, has been known for its crucial role in the pathogenesis of these rheumatic autoimmune diseases. In addition to regulating lymphocyte proliferation and antibody synthesis, prolactin is also responsible for regulating cytokine production. Moreover, it contributes to the breakdown of central and peripheral tolerance mechanisms of B lymphocytes. Given the crucial role of prolactin in the pathogenesis of the mentioned RADs, prolactin may contribute to their pathogenesis by the breakdown of tolerance. In the present study, the key role of prolactin to the breakdown of B lymphocyte tolerance and its possible implication for the pathogenesis of these diseases is discussed. Current literature supports prolactin's role in the breakdown of B lymphocyte central and peripheral tolerance mechanisms, such apoptosis, receptor editing, and also anergy. Therefore, prolactin may contribute to the pathogenesis of RADs by the breakdown of B lymphocyte tolerance. However, more investigations, particularly in RA and SSc animal models, are required to precisely address the pathologic role of prolactin.
Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) are the most common rheumatic autoimmune diseases/disorders (RADs) that affect autologous connective tissues as a result of the breakdown of the self-tolerance mechanisms of the immune system. Prolactin, a glycoprotein hormone, has been known for its crucial role in the pathogenesis of these rheumatic autoimmune diseases. In addition to regulating lymphocyte proliferation and antibody synthesis, prolactin is also responsible for regulating cytokine production. Moreover, it contributes to the breakdown of central and peripheral tolerance mechanisms of B lymphocytes. Given the crucial role of prolactin in the pathogenesis of the mentioned RADs, prolactin may contribute to their pathogenesis by the breakdown of tolerance. In the present study, the key role of prolactin to the breakdown of B lymphocyte tolerance and its possible implication for the pathogenesis of these diseases is discussed. Current literature supports prolactin's role in the breakdown of B lymphocyte central and peripheral tolerance mechanisms, such apoptosis, receptor editing, and also anergy. Therefore, prolactin may contribute to the pathogenesis of RADs by the breakdown of B lymphocyte tolerance. However, more investigations, particularly in RA and SSc animal models, are required to precisely address the pathologic role of prolactin.Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) are the most common rheumatic autoimmune diseases/disorders (RADs) that affect autologous connective tissues as a result of the breakdown of the self-tolerance mechanisms of the immune system. Prolactin, a glycoprotein hormone, has been known for its crucial role in the pathogenesis of these rheumatic autoimmune diseases. In addition to regulating lymphocyte proliferation and antibody synthesis, prolactin is also responsible for regulating cytokine production. Moreover, it contributes to the breakdown of central and peripheral tolerance mechanisms of B lymphocytes. Given the crucial role of prolactin in the pathogenesis of the mentioned RADs, prolactin may contribute to their pathogenesis by the breakdown of tolerance. In the present study, the key role of prolactin to the breakdown of B lymphocyte tolerance and its possible implication for the pathogenesis of these diseases is discussed. Current literature supports prolactin's role in the breakdown of B lymphocyte central and peripheral tolerance mechanisms, such apoptosis, receptor editing, and also anergy. Therefore, prolactin may contribute to the pathogenesis of RADs by the breakdown of B lymphocyte tolerance. However, more investigations, particularly in RA and SSc animal models, are required to precisely address the pathologic role of prolactin.
ArticleNumber e16977
Author Mousavi, Mohammad Javad
Ghotloo, Somayeh
Alizadeh, Ardalan
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Cites_doi 10.1007/978-3-319-12114-7_4
10.1007/s10067-020-05549-8
10.1111/j.1365-2265.1976.tb03867.x
10.1073/pnas.96.4.1246
10.1191/096120398678920334
10.1007/s12026-016-8891-x
10.1021/bi00755a030
10.1016/0303-7207(95)03738-1
10.1186/s40695-015-0012-9
10.1007/s00296-009-1284-x
10.1186/ar586
10.1111/j.1346-8138.2009.00762.x
10.1159/000237242
10.1196/annals.1351.023
10.1111/j.1365-2249.2009.04007.x
10.1196/annals.1422.024
10.3389/fimmu.2018.00073
10.1016/j.jneuroim.2014.02.007
10.1155/2013/287469
10.1007/s12079-012-0168-0
10.1016/j.biopha.2004.04.007
10.1177/0961203315622276
10.1002/art.24500
10.1186/1471-2172-13-11
10.1371/journal.pone.0031305
10.1093/rheumatology/kew316
10.1007/s10067-015-2904-3
10.1191/096120301717164895
10.1016/j.autrev.2012.05.011
10.1016/j.biopha.2006.02.007
10.1093/intimm/dxm145
10.1002/art.38098
10.1080/00325481.2017.1241130
10.1080/00325481.2019.1559430
10.1007/s10067-020-05526-1
10.1016/j.bcp.2020.114360
10.1155/2016/3219017
10.1093/rheumatology/kei111
10.1007/s11926-015-0505-4
10.1177/0961203317693094
10.1016/S0140-6736(16)30173-8
10.1093/protein/8.12.1215
10.1111/j.1471-0528.1976.tb00913.x
10.3389/fimmu.2015.00167
10.1016/S0303-7207(97)00063-4
10.1097/MD.0000000000022239
10.3389/fimmu.2017.00720
10.1191/096120301717164912
10.1038/nri1604
10.1111/j.1749-6632.2002.tb04224.x
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Issue 6
Keywords B lymphocyte tolerance
B lymphocyte
Tolerance
Autoimmune disease
Rheumatic autoimmune disease
Prolactin
Language English
License This is an open access article under the CC BY-NC-ND license.
2023 The Authors.
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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References Mirone, Barini, Barini (bib31) 2006; 1069
Walport (bib37) 2002; 4
Tang (bib13) 2017; 8
Flores-Fernández (bib22) 2016; 2016
Hamaguchi (bib52) 2010; 37
Biswas, Rodeck (bib11) 1976; 83
Wu (bib44) 2021; 183
Tripathi, Sodhi (bib17) 2008; 20
Jara (bib41) 2017; 65
Goffin, Martial, Summers (bib4) 1995; 8
Zendman, van Venrooij, Pruijn (bib43) 2005; 45
Marder, Vinet, Somers (bib35) 2015; 1
Franchimont (bib10) 1976; 5
van den Hoogen (bib51) 2013; 65
Tang (bib47) 2017; 8
Radhakrishnan (bib5) 2012; 6
Wu (bib34) 2020; 99
Kill, Riemekasten (bib50) 2015; 17
Saha (bib24) 2009; 60
Feng, Li, Jiang (bib48) 2021; 40
Bewley, Li (bib3) 1972; 11
Lee, Bae, Song (bib45) 2015; 34
McMurray (bib40) 1995; 22
Platanias (bib55) 2005; 5
Wu (bib28) 2019; 131
Pezet (bib6) 1997; 129
Ledesma-Soto (bib20) 2012; 13
Alvarez-Nemegyei (bib39) 1998; 7
Song, Lee (bib26) 2017; 26
Czuwara-Ladykowska (bib32) 2006; 60
DaSilva (bib7) 1996; 117
Seriolo (bib30) 2002; 966
Yang (bib19) 2016; 25
Moisini, Davidson (bib54) 2009; 158
Clapp (bib2) 2015; 846
Tang (bib46) 2016; 55
Struman (bib1) 1999; 96
Smolen, Aletaha, McInnes (bib42) 2016; 388
Kayser, Fritzler (bib49) 2015; 6
Fojtíková (bib29) 2010; 28
Roelfsema (bib9) 2012; 7
Buckley (bib15) 2001; 10
Mehra (bib53) 2013; 12
Ostrom (bib8) 1990; 14
Wang (bib25) 2017; 129
Peeva (bib12) 2004; 58
Abbas, Lichtman, Pillai (bib36) 2017
Fojtíková (bib33) 2010; 30
Jara (bib27) 2007; 1108
Chaichian, Strand (bib38) 2021; 40
Montgomery (bib14) 2001; 10
Correale, Farez, Ysrraelit (bib23) 2014; 269
Borba, Zandman-Goddard, Shoenfeld (bib16) 2018; 9
Gutiérrez (bib18) 1996; 109
Legorreta-Haquet (bib21) 2013; 2013
Roelfsema (10.1016/j.heliyon.2023.e16977_bib9) 2012; 7
Tang (10.1016/j.heliyon.2023.e16977_bib47) 2017; 8
Flores-Fernández (10.1016/j.heliyon.2023.e16977_bib22) 2016; 2016
van den Hoogen (10.1016/j.heliyon.2023.e16977_bib51) 2013; 65
Wu (10.1016/j.heliyon.2023.e16977_bib28) 2019; 131
Goffin (10.1016/j.heliyon.2023.e16977_bib4) 1995; 8
Bewley (10.1016/j.heliyon.2023.e16977_bib3) 1972; 11
McMurray (10.1016/j.heliyon.2023.e16977_bib40) 1995; 22
Gutiérrez (10.1016/j.heliyon.2023.e16977_bib18) 1996; 109
Radhakrishnan (10.1016/j.heliyon.2023.e16977_bib5) 2012; 6
Ledesma-Soto (10.1016/j.heliyon.2023.e16977_bib20) 2012; 13
Jara (10.1016/j.heliyon.2023.e16977_bib27) 2007; 1108
Zendman (10.1016/j.heliyon.2023.e16977_bib43) 2005; 45
Seriolo (10.1016/j.heliyon.2023.e16977_bib30) 2002; 966
Alvarez-Nemegyei (10.1016/j.heliyon.2023.e16977_bib39) 1998; 7
Tang (10.1016/j.heliyon.2023.e16977_bib13) 2017; 8
Smolen (10.1016/j.heliyon.2023.e16977_bib42) 2016; 388
Borba (10.1016/j.heliyon.2023.e16977_bib16) 2018; 9
Tripathi (10.1016/j.heliyon.2023.e16977_bib17) 2008; 20
Czuwara-Ladykowska (10.1016/j.heliyon.2023.e16977_bib32) 2006; 60
Biswas (10.1016/j.heliyon.2023.e16977_bib11) 1976; 83
Song (10.1016/j.heliyon.2023.e16977_bib26) 2017; 26
Wu (10.1016/j.heliyon.2023.e16977_bib44) 2021; 183
Moisini (10.1016/j.heliyon.2023.e16977_bib54) 2009; 158
Pezet (10.1016/j.heliyon.2023.e16977_bib6) 1997; 129
Peeva (10.1016/j.heliyon.2023.e16977_bib12) 2004; 58
Feng (10.1016/j.heliyon.2023.e16977_bib48) 2021; 40
Fojtíková (10.1016/j.heliyon.2023.e16977_bib33) 2010; 30
Jara (10.1016/j.heliyon.2023.e16977_bib41) 2017; 65
Fojtíková (10.1016/j.heliyon.2023.e16977_bib29) 2010; 28
Abbas (10.1016/j.heliyon.2023.e16977_bib36) 2017
Hamaguchi (10.1016/j.heliyon.2023.e16977_bib52) 2010; 37
Mehra (10.1016/j.heliyon.2023.e16977_bib53) 2013; 12
Clapp (10.1016/j.heliyon.2023.e16977_bib2) 2015; 846
Chaichian (10.1016/j.heliyon.2023.e16977_bib38) 2021; 40
Struman (10.1016/j.heliyon.2023.e16977_bib1) 1999; 96
Kill (10.1016/j.heliyon.2023.e16977_bib50) 2015; 17
Platanias (10.1016/j.heliyon.2023.e16977_bib55) 2005; 5
Mirone (10.1016/j.heliyon.2023.e16977_bib31) 2006; 1069
Saha (10.1016/j.heliyon.2023.e16977_bib24) 2009; 60
Wang (10.1016/j.heliyon.2023.e16977_bib25) 2017; 129
Kayser (10.1016/j.heliyon.2023.e16977_bib49) 2015; 6
Tang (10.1016/j.heliyon.2023.e16977_bib46) 2016; 55
Franchimont (10.1016/j.heliyon.2023.e16977_bib10) 1976; 5
Yang (10.1016/j.heliyon.2023.e16977_bib19) 2016; 25
Ostrom (10.1016/j.heliyon.2023.e16977_bib8) 1990; 14
DaSilva (10.1016/j.heliyon.2023.e16977_bib7) 1996; 117
Lee (10.1016/j.heliyon.2023.e16977_bib45) 2015; 34
Wu (10.1016/j.heliyon.2023.e16977_bib34) 2020; 99
Walport (10.1016/j.heliyon.2023.e16977_bib37) 2002; 4
Buckley (10.1016/j.heliyon.2023.e16977_bib15) 2001; 10
Correale (10.1016/j.heliyon.2023.e16977_bib23) 2014; 269
Montgomery (10.1016/j.heliyon.2023.e16977_bib14) 2001; 10
Marder (10.1016/j.heliyon.2023.e16977_bib35) 2015; 1
Legorreta-Haquet (10.1016/j.heliyon.2023.e16977_bib21) 2013; 2013
References_xml – volume: 8
  start-page: 1215
  year: 1995
  end-page: 1231
  ident: bib4
  article-title: Use of a model to understand prolactin and growth hormone specificities
  publication-title: Protein Eng. Des. Sel.
– volume: 60
  start-page: 1743
  year: 2009
  end-page: 1752
  ident: bib24
  article-title: Prolactin alters the mechanisms of B cell tolerance induction
  publication-title: Arthritis Rheum.
– volume: 966
  start-page: 258
  year: 2002
  end-page: 262
  ident: bib30
  article-title: Serum prolactin concentrations in male patients with rheumatoid arthritis
  publication-title: Ann. N. Y. Acad. Sci.
– volume: 6
  start-page: 167
  year: 2015
  ident: bib49
  article-title: Autoantibodies in systemic sclerosis: unanswered questions
  publication-title: Front. Immunol.
– volume: 30
  start-page: 1691
  year: 2010
  end-page: 1693
  ident: bib33
  article-title: Polymorphism of the extrapituitary prolactin promoter and systemic sclerosis
  publication-title: Rheumatol. Int.
– volume: 58
  start-page: 310
  year: 2004
  end-page: 319
  ident: bib12
  article-title: Prolactin as a modulator of B cell function: implications for SLE
  publication-title: Biomed. Pharmacother.
– volume: 26
  start-page: 1260
  year: 2017
  end-page: 1268
  ident: bib26
  article-title: Circulating prolactin level in systemic lupus erythematosus and its correlation with disease activity: a meta-analysis
  publication-title: Lupus
– volume: 109
  start-page: 229
  year: 1996
  end-page: 235
  ident: bib18
  article-title: Prolactin-induced immunoglobulin and autoantibody production by peripheral blood mononuclear cells from systemic lupus erythematosus and normal individuals
  publication-title: Int. Arch. Allergy Immunol.
– volume: 131
  start-page: 156
  year: 2019
  end-page: 162
  ident: bib28
  article-title: Circulating levels of prolactin are elevated in patients with rheumatoid arthritis: a meta-analysis
  publication-title: Postgrad. Med.
– volume: 25
  start-page: 513
  year: 2016
  end-page: 519
  ident: bib19
  article-title: Increased serum level of prolactin is related to autoantibody production in systemic lupus erythematosus
  publication-title: Lupus
– volume: 269
  start-page: 76
  year: 2014
  end-page: 86
  ident: bib23
  article-title: Role of prolactin in B cell regulation in multiple sclerosis
  publication-title: J. Neuroimmunol.
– volume: 6
  start-page: 169
  year: 2012
  end-page: 173
  ident: bib5
  article-title: A pathway map of prolactin signaling
  publication-title: Journal of cell communication and signaling
– volume: 45
  start-page: 20
  year: 2005
  end-page: 25
  ident: bib43
  article-title: Use and significance of anti-CCP autoantibodies in rheumatoid arthritis
  publication-title: Rheumatology
– volume: 14
  start-page: 1
  year: 1990
  end-page: 43
  ident: bib8
  article-title: A review of the hormone prolactin during lactation
  publication-title: Prog. Food Nutr. Sci.
– volume: 37
  start-page: 42
  year: 2010
  end-page: 53
  ident: bib52
  article-title: Autoantibody profiles in systemic sclerosis: predictive value for clinical evaluation and prognosis
  publication-title: J. Dermatol.
– volume: 5
  start-page: 375
  year: 2005
  end-page: 386
  ident: bib55
  article-title: Mechanisms of type-I- and type-II-interferon-mediated signalling
  publication-title: Nat. Rev. Immunol.
– volume: 10
  start-page: 665
  year: 2001
  end-page: 675
  ident: bib14
  article-title: Prolactin production by immune cells
  publication-title: Lupus
– volume: 65
  start-page: 512
  year: 2017
  end-page: 523
  ident: bib41
  article-title: Prolactin has a pathogenic role in systemic lupus erythematosus
  publication-title: Immunol. Res.
– volume: 83
  start-page: 683
  year: 1976
  end-page: 687
  ident: bib11
  article-title: Plasma prolactin levels during pregnancy
  publication-title: Br. J. Obstet. Gynaecol.
– volume: 65
  start-page: 2737
  year: 2013
  end-page: 2747
  ident: bib51
  article-title: 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative
  publication-title: Arthritis Rheum.
– volume: 7
  year: 2012
  ident: bib9
  article-title: Prolactin secretion in healthy adults is determined by gender, age and body mass index
  publication-title: PLoS One
– volume: 60
  start-page: 152
  year: 2006
  end-page: 155
  ident: bib32
  article-title: Prolactin synthesis by lymphocytes from patients with systemic sclerosis
  publication-title: Biomed. Pharmacother.
– volume: 9
  start-page: 73
  year: 2018
  ident: bib16
  article-title: Prolactin and autoimmunity
  publication-title: Front. Immunol.
– volume: 10
  start-page: 684
  year: 2001
  end-page: 690
  ident: bib15
  article-title: Prolactin, a lymphocyte growth and survival factor
  publication-title: Lupus
– volume: 117
  start-page: 131
  year: 1996
  end-page: 140
  ident: bib7
  article-title: Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580
  publication-title: Mol. Cell. Endocrinol.
– volume: 158
  start-page: 155
  year: 2009
  end-page: 163
  ident: bib54
  article-title: BAFF: a local and systemic target in autoimmune diseases
  publication-title: Clin. Exp. Immunol.
– volume: 183
  year: 2021
  ident: bib44
  article-title: The prospects for targeting FcR as a novel therapeutic strategy in rheumatoid arthritis
  publication-title: Biochem. Pharmacol.
– volume: 388
  start-page: 2023
  year: 2016
  end-page: 2038
  ident: bib42
  article-title: Rheumatoid arthritis
  publication-title: Lancet
– volume: 12
  start-page: 340
  year: 2013
  end-page: 354
  ident: bib53
  article-title: Autoantibodies in systemic sclerosis
  publication-title: Autoimmun. Rev.
– volume: 20
  start-page: 327
  year: 2008
  end-page: 336
  ident: bib17
  article-title: Prolactin-induced production of cytokines in macrophages in vitro involves JAK/STAT and JNK MAPK pathways
  publication-title: Int. Immunol.
– volume: 4
  start-page: S279
  year: 2002
  end-page: S293
  ident: bib37
  article-title: Complement and systemic lupus erythematosus
  publication-title: Arthritis Res.
– volume: 2016
  year: 2016
  ident: bib22
  article-title: Prolactin rescues immature B-cells from apoptosis induced by B-cell receptor cross-linking
  publication-title: J. Immunol. Res.
– volume: 129
  start-page: 126
  year: 2017
  end-page: 132
  ident: bib25
  article-title: Increased plasma/serum levels of prolactin in systemic lupus erythematosus: a systematic review and meta-analysis
  publication-title: Postgrad. Med.
– volume: 11
  start-page: 884
  year: 1972
  end-page: 888
  ident: bib3
  article-title: Circular dichroism studies on human pituitary growth hormone and ovine pituitary lactogenic hormone
  publication-title: Biochemistry
– volume: 1108
  start-page: 218
  year: 2007
  end-page: 226
  ident: bib27
  article-title: Prolactin levels are associated with lupus activity, lupus anticoagulant, and poor outcome in pregnancy
  publication-title: Ann. N. Y. Acad. Sci.
– year: 2017
  ident: bib36
  article-title: Cellular and Molecular Immunology
– volume: 28
  start-page: 849
  year: 2010
  end-page: 854
  ident: bib29
  article-title: Elevated prolactin levels in patients with rheumatoid arthritis: association with disease activity and structural damage
  publication-title: Clin. Exp. Rheumatol.
– volume: 2013
  year: 2013
  ident: bib21
  article-title: Prolactin levels correlate with abnormal B cell maturation in MRL and MRL/lpr mouse models of systemic lupus erythematosus-like disease
  publication-title: Clin. Dev. Immunol.
– volume: 96
  start-page: 1246
  year: 1999
  end-page: 1251
  ident: bib1
  article-title: Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
– volume: 129
  start-page: 199
  year: 1997
  end-page: 208
  ident: bib6
  article-title: The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor
  publication-title: Mol. Cell. Endocrinol.
– volume: 13
  start-page: 11
  year: 2012
  ident: bib20
  article-title: Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment
  publication-title: BMC Immunol.
– volume: 40
  start-page: 3027
  year: 2021
  end-page: 3037
  ident: bib38
  article-title: Interferon-directed therapies for the treatment of systemic lupus erythematosus: a critical update
  publication-title: Clin. Rheumatol.
– volume: 7
  start-page: 414
  year: 1998
  end-page: 419
  ident: bib39
  article-title: Bromocriptine in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled study
  publication-title: Lupus
– volume: 8
  start-page: 720
  year: 2017
  ident: bib47
  article-title: Insight into the endocrine system and the immune system: a review of the inflammatory role of prolactin in rheumatoid arthritis and psoriatic arthritis
  publication-title: Front. Immunol.
– volume: 34
  start-page: 683
  year: 2015
  end-page: 690
  ident: bib45
  article-title: Meta-analysis of associations between functional prolactin-1149 G/T polymorphism and susceptibility to rheumatoid arthritis and systemic lupus erythematosus
  publication-title: Clin. Rheumatol.
– volume: 8
  start-page: 720
  year: 2017
  ident: bib13
  article-title: Insight into the endocrine system and the immune system: a review of the inflammatory role of prolactin in rheumatoid arthritis and psoriatic arthritis
  publication-title: Front. Immunol.
– volume: 1
  year: 2015
  ident: bib35
  article-title: Rheumatic autoimmune diseases in women and midlife health
  publication-title: Womens Midlife Health
– volume: 40
  start-page: 3039
  year: 2021
  end-page: 3051
  ident: bib48
  article-title: Prevalence and predictors of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review and meta-analysis
  publication-title: Clin. Rheumatol.
– volume: 846
  start-page: 83
  year: 2015
  end-page: 95
  ident: bib2
  article-title: Regulation of blood vessels by prolactin and vasoinhibins
  publication-title: Adv. Exp. Med. Biol.
– volume: 5
  start-page: 643
  year: 1976
  end-page: 650
  ident: bib10
  article-title: Prolactin levels during the menstrual cycle
  publication-title: Clin. Endocrinol.
– volume: 22
  start-page: 2084
  year: 1995
  end-page: 2091
  ident: bib40
  article-title: Efficacy of bromocriptine in an open label therapeutic trial for systemic lupus erythematosus
  publication-title: J. Rheumatol.
– volume: 99
  year: 2020
  ident: bib34
  article-title: Elevated plasma/serum levels of prolactin in patients with systemic sclerosis: a systematic review and meta-analysis
  publication-title: Medicine
– volume: 55
  start-page: 2248
  year: 2016
  end-page: 2259
  ident: bib46
  article-title: The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation
  publication-title: Rheumatology
– volume: 1069
  start-page: 257
  year: 2006
  end-page: 262
  ident: bib31
  article-title: Androgen and prolactin (Prl) levels in systemic sclerosis (SSc): relationship to disease severity
  publication-title: Ann. N. Y. Acad. Sci.
– volume: 17
  start-page: 34
  year: 2015
  ident: bib50
  article-title: Functional autoantibodies in systemic sclerosis pathogenesis
  publication-title: Curr. Rheumatol. Rep.
– volume: 846
  start-page: 83
  year: 2015
  ident: 10.1016/j.heliyon.2023.e16977_bib2
  article-title: Regulation of blood vessels by prolactin and vasoinhibins
  publication-title: Adv. Exp. Med. Biol.
  doi: 10.1007/978-3-319-12114-7_4
– volume: 40
  start-page: 3039
  issue: 8
  year: 2021
  ident: 10.1016/j.heliyon.2023.e16977_bib48
  article-title: Prevalence and predictors of small intestinal bacterial overgrowth in systemic sclerosis: a systematic review and meta-analysis
  publication-title: Clin. Rheumatol.
  doi: 10.1007/s10067-020-05549-8
– volume: 5
  start-page: 643
  issue: 6
  year: 1976
  ident: 10.1016/j.heliyon.2023.e16977_bib10
  article-title: Prolactin levels during the menstrual cycle
  publication-title: Clin. Endocrinol.
  doi: 10.1111/j.1365-2265.1976.tb03867.x
– volume: 96
  start-page: 1246
  issue: 4
  year: 1999
  ident: 10.1016/j.heliyon.2023.e16977_bib1
  article-title: Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis
  publication-title: Proc. Natl. Acad. Sci. U. S. A.
  doi: 10.1073/pnas.96.4.1246
– volume: 7
  start-page: 414
  issue: 6
  year: 1998
  ident: 10.1016/j.heliyon.2023.e16977_bib39
  article-title: Bromocriptine in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled study
  publication-title: Lupus
  doi: 10.1191/096120398678920334
– volume: 65
  start-page: 512
  issue: 2
  year: 2017
  ident: 10.1016/j.heliyon.2023.e16977_bib41
  article-title: Prolactin has a pathogenic role in systemic lupus erythematosus
  publication-title: Immunol. Res.
  doi: 10.1007/s12026-016-8891-x
– volume: 11
  start-page: 884
  issue: 5
  year: 1972
  ident: 10.1016/j.heliyon.2023.e16977_bib3
  article-title: Circular dichroism studies on human pituitary growth hormone and ovine pituitary lactogenic hormone
  publication-title: Biochemistry
  doi: 10.1021/bi00755a030
– volume: 117
  start-page: 131
  issue: 2
  year: 1996
  ident: 10.1016/j.heliyon.2023.e16977_bib7
  article-title: Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580
  publication-title: Mol. Cell. Endocrinol.
  doi: 10.1016/0303-7207(95)03738-1
– volume: 1
  year: 2015
  ident: 10.1016/j.heliyon.2023.e16977_bib35
  article-title: Rheumatic autoimmune diseases in women and midlife health
  publication-title: Womens Midlife Health
  doi: 10.1186/s40695-015-0012-9
– volume: 30
  start-page: 1691
  issue: 12
  year: 2010
  ident: 10.1016/j.heliyon.2023.e16977_bib33
  article-title: Polymorphism of the extrapituitary prolactin promoter and systemic sclerosis
  publication-title: Rheumatol. Int.
  doi: 10.1007/s00296-009-1284-x
– volume: 4
  start-page: S279
  issue: Suppl 3
  year: 2002
  ident: 10.1016/j.heliyon.2023.e16977_bib37
  article-title: Complement and systemic lupus erythematosus
  publication-title: Arthritis Res.
  doi: 10.1186/ar586
– volume: 37
  start-page: 42
  issue: 1
  year: 2010
  ident: 10.1016/j.heliyon.2023.e16977_bib52
  article-title: Autoantibody profiles in systemic sclerosis: predictive value for clinical evaluation and prognosis
  publication-title: J. Dermatol.
  doi: 10.1111/j.1346-8138.2009.00762.x
– volume: 109
  start-page: 229
  issue: 3
  year: 1996
  ident: 10.1016/j.heliyon.2023.e16977_bib18
  article-title: Prolactin-induced immunoglobulin and autoantibody production by peripheral blood mononuclear cells from systemic lupus erythematosus and normal individuals
  publication-title: Int. Arch. Allergy Immunol.
  doi: 10.1159/000237242
– volume: 1069
  start-page: 257
  year: 2006
  ident: 10.1016/j.heliyon.2023.e16977_bib31
  article-title: Androgen and prolactin (Prl) levels in systemic sclerosis (SSc): relationship to disease severity
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1196/annals.1351.023
– volume: 158
  start-page: 155
  issue: 2
  year: 2009
  ident: 10.1016/j.heliyon.2023.e16977_bib54
  article-title: BAFF: a local and systemic target in autoimmune diseases
  publication-title: Clin. Exp. Immunol.
  doi: 10.1111/j.1365-2249.2009.04007.x
– volume: 1108
  start-page: 218
  year: 2007
  ident: 10.1016/j.heliyon.2023.e16977_bib27
  article-title: Prolactin levels are associated with lupus activity, lupus anticoagulant, and poor outcome in pregnancy
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1196/annals.1422.024
– volume: 9
  start-page: 73
  year: 2018
  ident: 10.1016/j.heliyon.2023.e16977_bib16
  article-title: Prolactin and autoimmunity
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2018.00073
– volume: 269
  start-page: 76
  issue: 1–2
  year: 2014
  ident: 10.1016/j.heliyon.2023.e16977_bib23
  article-title: Role of prolactin in B cell regulation in multiple sclerosis
  publication-title: J. Neuroimmunol.
  doi: 10.1016/j.jneuroim.2014.02.007
– volume: 2013
  year: 2013
  ident: 10.1016/j.heliyon.2023.e16977_bib21
  article-title: Prolactin levels correlate with abnormal B cell maturation in MRL and MRL/lpr mouse models of systemic lupus erythematosus-like disease
  publication-title: Clin. Dev. Immunol.
  doi: 10.1155/2013/287469
– volume: 6
  start-page: 169
  issue: 3
  year: 2012
  ident: 10.1016/j.heliyon.2023.e16977_bib5
  article-title: A pathway map of prolactin signaling
  publication-title: Journal of cell communication and signaling
  doi: 10.1007/s12079-012-0168-0
– volume: 58
  start-page: 310
  issue: 5
  year: 2004
  ident: 10.1016/j.heliyon.2023.e16977_bib12
  article-title: Prolactin as a modulator of B cell function: implications for SLE
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2004.04.007
– volume: 25
  start-page: 513
  issue: 5
  year: 2016
  ident: 10.1016/j.heliyon.2023.e16977_bib19
  article-title: Increased serum level of prolactin is related to autoantibody production in systemic lupus erythematosus
  publication-title: Lupus
  doi: 10.1177/0961203315622276
– volume: 60
  start-page: 1743
  issue: 6
  year: 2009
  ident: 10.1016/j.heliyon.2023.e16977_bib24
  article-title: Prolactin alters the mechanisms of B cell tolerance induction
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.24500
– volume: 13
  start-page: 11
  year: 2012
  ident: 10.1016/j.heliyon.2023.e16977_bib20
  article-title: Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment
  publication-title: BMC Immunol.
  doi: 10.1186/1471-2172-13-11
– year: 2017
  ident: 10.1016/j.heliyon.2023.e16977_bib36
– volume: 7
  issue: 2
  year: 2012
  ident: 10.1016/j.heliyon.2023.e16977_bib9
  article-title: Prolactin secretion in healthy adults is determined by gender, age and body mass index
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0031305
– volume: 55
  start-page: 2248
  issue: 12
  year: 2016
  ident: 10.1016/j.heliyon.2023.e16977_bib46
  article-title: The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation
  publication-title: Rheumatology
  doi: 10.1093/rheumatology/kew316
– volume: 34
  start-page: 683
  issue: 4
  year: 2015
  ident: 10.1016/j.heliyon.2023.e16977_bib45
  article-title: Meta-analysis of associations between functional prolactin-1149 G/T polymorphism and susceptibility to rheumatoid arthritis and systemic lupus erythematosus
  publication-title: Clin. Rheumatol.
  doi: 10.1007/s10067-015-2904-3
– volume: 10
  start-page: 665
  issue: 10
  year: 2001
  ident: 10.1016/j.heliyon.2023.e16977_bib14
  article-title: Prolactin production by immune cells
  publication-title: Lupus
  doi: 10.1191/096120301717164895
– volume: 28
  start-page: 849
  issue: 6
  year: 2010
  ident: 10.1016/j.heliyon.2023.e16977_bib29
  article-title: Elevated prolactin levels in patients with rheumatoid arthritis: association with disease activity and structural damage
  publication-title: Clin. Exp. Rheumatol.
– volume: 12
  start-page: 340
  issue: 3
  year: 2013
  ident: 10.1016/j.heliyon.2023.e16977_bib53
  article-title: Autoantibodies in systemic sclerosis
  publication-title: Autoimmun. Rev.
  doi: 10.1016/j.autrev.2012.05.011
– volume: 60
  start-page: 152
  issue: 4
  year: 2006
  ident: 10.1016/j.heliyon.2023.e16977_bib32
  article-title: Prolactin synthesis by lymphocytes from patients with systemic sclerosis
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2006.02.007
– volume: 20
  start-page: 327
  issue: 3
  year: 2008
  ident: 10.1016/j.heliyon.2023.e16977_bib17
  article-title: Prolactin-induced production of cytokines in macrophages in vitro involves JAK/STAT and JNK MAPK pathways
  publication-title: Int. Immunol.
  doi: 10.1093/intimm/dxm145
– volume: 65
  start-page: 2737
  issue: 11
  year: 2013
  ident: 10.1016/j.heliyon.2023.e16977_bib51
  article-title: 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative
  publication-title: Arthritis Rheum.
  doi: 10.1002/art.38098
– volume: 129
  start-page: 126
  issue: 1
  year: 2017
  ident: 10.1016/j.heliyon.2023.e16977_bib25
  article-title: Increased plasma/serum levels of prolactin in systemic lupus erythematosus: a systematic review and meta-analysis
  publication-title: Postgrad. Med.
  doi: 10.1080/00325481.2017.1241130
– volume: 131
  start-page: 156
  issue: 2
  year: 2019
  ident: 10.1016/j.heliyon.2023.e16977_bib28
  article-title: Circulating levels of prolactin are elevated in patients with rheumatoid arthritis: a meta-analysis
  publication-title: Postgrad. Med.
  doi: 10.1080/00325481.2019.1559430
– volume: 40
  start-page: 3027
  issue: 8
  year: 2021
  ident: 10.1016/j.heliyon.2023.e16977_bib38
  article-title: Interferon-directed therapies for the treatment of systemic lupus erythematosus: a critical update
  publication-title: Clin. Rheumatol.
  doi: 10.1007/s10067-020-05526-1
– volume: 183
  year: 2021
  ident: 10.1016/j.heliyon.2023.e16977_bib44
  article-title: The prospects for targeting FcR as a novel therapeutic strategy in rheumatoid arthritis
  publication-title: Biochem. Pharmacol.
  doi: 10.1016/j.bcp.2020.114360
– volume: 14
  start-page: 1
  issue: 1
  year: 1990
  ident: 10.1016/j.heliyon.2023.e16977_bib8
  article-title: A review of the hormone prolactin during lactation
  publication-title: Prog. Food Nutr. Sci.
– volume: 2016
  year: 2016
  ident: 10.1016/j.heliyon.2023.e16977_bib22
  article-title: Prolactin rescues immature B-cells from apoptosis induced by B-cell receptor cross-linking
  publication-title: J. Immunol. Res.
  doi: 10.1155/2016/3219017
– volume: 45
  start-page: 20
  issue: 1
  year: 2005
  ident: 10.1016/j.heliyon.2023.e16977_bib43
  article-title: Use and significance of anti-CCP autoantibodies in rheumatoid arthritis
  publication-title: Rheumatology
  doi: 10.1093/rheumatology/kei111
– volume: 17
  start-page: 34
  issue: 5
  year: 2015
  ident: 10.1016/j.heliyon.2023.e16977_bib50
  article-title: Functional autoantibodies in systemic sclerosis pathogenesis
  publication-title: Curr. Rheumatol. Rep.
  doi: 10.1007/s11926-015-0505-4
– volume: 22
  start-page: 2084
  issue: 11
  year: 1995
  ident: 10.1016/j.heliyon.2023.e16977_bib40
  article-title: Efficacy of bromocriptine in an open label therapeutic trial for systemic lupus erythematosus
  publication-title: J. Rheumatol.
– volume: 26
  start-page: 1260
  issue: 12
  year: 2017
  ident: 10.1016/j.heliyon.2023.e16977_bib26
  article-title: Circulating prolactin level in systemic lupus erythematosus and its correlation with disease activity: a meta-analysis
  publication-title: Lupus
  doi: 10.1177/0961203317693094
– volume: 388
  start-page: 2023
  issue: 10055
  year: 2016
  ident: 10.1016/j.heliyon.2023.e16977_bib42
  article-title: Rheumatoid arthritis
  publication-title: Lancet
  doi: 10.1016/S0140-6736(16)30173-8
– volume: 8
  start-page: 1215
  issue: 12
  year: 1995
  ident: 10.1016/j.heliyon.2023.e16977_bib4
  article-title: Use of a model to understand prolactin and growth hormone specificities
  publication-title: Protein Eng. Des. Sel.
  doi: 10.1093/protein/8.12.1215
– volume: 83
  start-page: 683
  issue: 9
  year: 1976
  ident: 10.1016/j.heliyon.2023.e16977_bib11
  article-title: Plasma prolactin levels during pregnancy
  publication-title: Br. J. Obstet. Gynaecol.
  doi: 10.1111/j.1471-0528.1976.tb00913.x
– volume: 6
  start-page: 167
  year: 2015
  ident: 10.1016/j.heliyon.2023.e16977_bib49
  article-title: Autoantibodies in systemic sclerosis: unanswered questions
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2015.00167
– volume: 129
  start-page: 199
  issue: 2
  year: 1997
  ident: 10.1016/j.heliyon.2023.e16977_bib6
  article-title: The last proline of Box 1 is essential for association with JAK2 and functional activation of the prolactin receptor
  publication-title: Mol. Cell. Endocrinol.
  doi: 10.1016/S0303-7207(97)00063-4
– volume: 99
  issue: 38
  year: 2020
  ident: 10.1016/j.heliyon.2023.e16977_bib34
  article-title: Elevated plasma/serum levels of prolactin in patients with systemic sclerosis: a systematic review and meta-analysis
  publication-title: Medicine
  doi: 10.1097/MD.0000000000022239
– volume: 8
  start-page: 720
  year: 2017
  ident: 10.1016/j.heliyon.2023.e16977_bib13
  article-title: Insight into the endocrine system and the immune system: a review of the inflammatory role of prolactin in rheumatoid arthritis and psoriatic arthritis
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2017.00720
– volume: 10
  start-page: 684
  issue: 10
  year: 2001
  ident: 10.1016/j.heliyon.2023.e16977_bib15
  article-title: Prolactin, a lymphocyte growth and survival factor
  publication-title: Lupus
  doi: 10.1191/096120301717164912
– volume: 5
  start-page: 375
  issue: 5
  year: 2005
  ident: 10.1016/j.heliyon.2023.e16977_bib55
  article-title: Mechanisms of type-I- and type-II-interferon-mediated signalling
  publication-title: Nat. Rev. Immunol.
  doi: 10.1038/nri1604
– volume: 8
  start-page: 720
  year: 2017
  ident: 10.1016/j.heliyon.2023.e16977_bib47
  article-title: Insight into the endocrine system and the immune system: a review of the inflammatory role of prolactin in rheumatoid arthritis and psoriatic arthritis
  publication-title: Front. Immunol.
  doi: 10.3389/fimmu.2017.00720
– volume: 966
  start-page: 258
  year: 2002
  ident: 10.1016/j.heliyon.2023.e16977_bib30
  article-title: Serum prolactin concentrations in male patients with rheumatoid arthritis
  publication-title: Ann. N. Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.2002.tb04224.x
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Snippet Systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic sclerosis (SSc) are the most common rheumatic autoimmune diseases/disorders (RADs)...
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SubjectTerms animals
antibodies
apoptosis
Autoimmune disease
B lymphocyte
B lymphocyte tolerance
B-lymphocytes
cytokines
glycoproteins
lupus erythematosus
lymphocyte proliferation
pathogenesis
Prolactin
Review
Rheumatic autoimmune disease
rheumatoid arthritis
sclerosis
Tolerance
Title Interference of B lymphocyte tolerance by prolactin in rheumatic autoimmune diseases
URI https://dx.doi.org/10.1016/j.heliyon.2023.e16977
https://www.ncbi.nlm.nih.gov/pubmed/37332964
https://www.proquest.com/docview/2827666519
https://www.proquest.com/docview/3040384194
https://pubmed.ncbi.nlm.nih.gov/PMC10276217
https://doaj.org/article/e73fe0d147544e69a52623ba74530901
Volume 9
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