Statistical Research on Marine Natural Products Based on Data Obtained between 1985 and 2008

• Published in: Marine drugs Vol. 9; no. 4; pp. 514 - 525
• Main Authors: Hu, Gu-Ping, Yuan, Jie, Sun, Li, She, Zhi-Gang, Wu, Jue-Heng, Lan, Xiu-Jian, Zhu, Xun, Lin, Yong-Cheng, Chen, Sheng-Ping
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2011; Molecular Diversity Preservation International
• Subjects: Algae; Animals; Aquatic Organisms - metabolism; Biological Products - chemistry; Biological Products - isolation & purification; Biological Products - pharmacology; Databases, Factual; Drug Discovery; Ethers; Invertebrates - metabolism; Marine Biology; Marine invertebrates; Marine microorganisms; marine natural products; Marine organisms; Microorganisms; novel compounds; Peptides; Phenols; Phytoplankton; Phytoplankton - metabolism; quantitative analysis; quantitative analysis; novel compounds; marine natural products
• ISSN: 1660-3397; 1660-3397
• DOI: 10.3390/md9040514

Since the 1960s, more than 20,000 compounds were discovered from marine organisms. In this paper we performed a quantitative analysis for the novel marine natural products reported between 1985 and 2008. The data was extracted mainly from the reviews of Faulkner and Blunt [1–26]. The organisms producing these marine natural products are divided into three major biological classes: marine microorganisms (including phytoplankton), marine algae and marine invertebrate. The marine natural products are divided into seven classes based on their chemical structure: terpenoids, steroids (including steroidal saponins), alkaloids, ethers (including ketals), phenols (including quinones), strigolactones, and peptides. The distribution and the temporal trend of these classes (biological classes and chemical structure classes) were investigated. We hope this article provides a comprehensive perspective on the research of marine natural products.