Transition to Fast Whole-Body SPECT/CT Bone Imaging: An Assessment of Image Quality

To investigate the impact of reduced SPECT acquisition time on reconstructed image quality for diagnostic purposes. Data from five patients referred for a routine bone SPECT/CT using the standard multi-bed SPECT/CT protocol were reviewed. The acquisition time was 900 s using gating technique; SPECT...

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Bibliographic Details
Published inDiagnostics (Basel) Vol. 12; no. 12; p. 2938
Main Authors Alqahtani, Mansour, Willowson, Kathy, Fulton, Roger, Constable, Chris, Kench, Peter
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 24.11.2022
MDPI
Subjects
acquisition time
bone imaging
Bones
CT imaging
Drug dosages
image reconstruction
Medical examination
Methods
Nuclear medicine
Patients
PET imaging
resolution recovery
Software
SPECT/CT
Tomography
Australia
United States > US
resolution recovery
bone imaging
image reconstruction
SPECT/CT
acquisition time
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Summary:To investigate the impact of reduced SPECT acquisition time on reconstructed image quality for diagnostic purposes. Data from five patients referred for a routine bone SPECT/CT using the standard multi-bed SPECT/CT protocol were reviewed. The acquisition time was 900 s using gating technique; SPECT date was resampled into reduced data sets of 480 s, 450 s, 360 s and 180 s acquisition duration per bed position. Each acquisition time was reconstructed using a fixed number of subsets (8 subsets) and 4, 8, 12, and 16 iterations, followed by a post-reconstruction 3D Gaussian filter of 8 mm FWHM. Two Nuclear Medicine physicians analysed all images independently to score image quality, noise and diagnostic confidence based on a pre-defined 4-point scale. Our result showed that the most frequently selected categories for 480 s and 450 s images were good image quality, average noise and fair confidence, particularly at lower iteration numbers 4 and 8. For the shortened acquisition time of 360 s and 180 s, statistical significance was observed in most reconstructed images compared with 900 s. The SPECT/CT can significantly shorten the acquisition time with maintained image quality, noise and diagnostic confidence. Therefore, acquiring data over 480 s and 450 s is feasible for WB-SPECT/CT bone scans to provide an optimal balance between acquisition time and image quality.
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ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics12122938