The contribution of the adrenal gland to the total amount of progesterone produced in the female rat
1. The amount of progesterone contained in both adrenal glands of a rat was similar to or larger than the amount of progesterone in the ovaries of the same rat. This was found in unstressed rats, in stressed rats and also in pregnant rats. 2. After ether anaesthesia and exsanguination the adrenal pr...
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Published in | The Journal of physiology Vol. 214; no. 1; pp. 115 - 126 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
England
The Physiological Society
01.04.1971
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Subjects | |
Online Access | Get full text |
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Summary: | 1. The amount of progesterone contained in both adrenal glands of a rat was similar to or larger than the amount of progesterone
in the ovaries of the same rat. This was found in unstressed rats, in stressed rats and also in pregnant rats.
2. After ether anaesthesia and exsanguination the adrenal progesterone content was increased by 75%; the ovarian progesterone
content remained unchanged.
3. In contrast, prolonged operative stress resulted in a rise in the ovarian content of progesterone and 20-dihydroprogesterone
whereas the adrenal progesterone content of these rats was lower than that of unstressed rats.
4. The rate at which progesterone was secreted by the adrenal glands of stressed rats was similar to the ovarian progesterone
secretion rate. Rats which were kept under mild stress conditions before the experiment showed higher adrenal progesterone
secretion rates. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0022-3751 1469-7793 |
DOI: | 10.1113/jphysiol.1971.sp009422 |