Cerebral Hemiatrophy in Systemic Lupus Erythematosus: Report of a Case

• Published in: Japanese Journal of Medicine Vol. 29; no. 4; pp. 423 - 428
• Main Authors: HlROHATA, Shunsei, MOROI, Yasuoki, YOSHINOYA, Sadayoshi, ISHIZAKA, Nobukazu, MIYAMOTO, Terumasa, MOMOSE, Toshimitsu
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 1990
• Subjects: Adolescent; Atrophy - diagnosis; Atrophy - etiology; Brain - pathology; Central nervous system; Cerebrospinal Fluid - immunology; Computed axial tomography; Crossed cerebellar diaschisis; Electroencephalography; Female; Humans; Lupus Erythematosus, Systemic - complications; Lupus Erythematosus, Systemic - diagnosis; Meningoencephalitis - complications; Neurocognitive Disorders - complications; Tomography, Emission-Computed, Single-Photon
• ISSN: 0021-5120; 1881-123X
• DOI: 10.2169/internalmedicine1962.29.423

An 18-year-old womanwith systemic lupus erythematosus developed neuropsychiatric disorders, including aseptic meningoencephalitis, organic brain syndrome and seizure. Aseries of computedaxial tomography scans revealed the progression of marked atrophy of the right cerebral hemisphere for a period of 3 years without occlusion or stenosis of large vessels on cerebral angiography. 1-123 IMP single photon emission computed tomography disclosed a markedly decreased uptake of 1-123 IMP in the right cerebral hemisphere, and also in the left cerebellar hemisphere (crossed cerebellar diaschisis), which disappeared within 2 years.