Overnight corneal swelling with high and low powered silicone hydrogel lenses

• Published in: Journal of optometry Vol. 8; no. 1; pp. 19 - 26
• Main Authors: Moezzi, Amir M, Fonn, Desmond, Varikooty, Jalaiah, Simpson, Trefford L
• Format: Journal Article
• Language: English
• Published: Spain Elsevier Espana 01.01.2015; Elsevier
• Subjects: Adolescent; Adult; Analysis of Variance; Contact Lenses, Extended-Wear - adverse effects; Contact Lenses, Hydrophilic - adverse effects; Corneal Edema - etiology; Corneal Edema - pathology; Corneal swelling; Corneal thickness; Edema corneal; espesor de la córnea; Female; Humans; Hydrogels - adverse effects; lentes de hidrogel de silicona; Male; Middle Aged; Ophthalmology; Optical pachometry; Original; Oxygen transmissibility; paquimetría óptica; Silicone Elastomers - adverse effects; Silicone hydrogel lenses; transmisibilidad del oxígeno; Young Adult; transmisibilidad del oxígeno; paquimetría óptica; espesor de la córnea; Silicone hydrogel lenses; Optical pachometry; Edema corneal; Corneal swelling; lentes de hidrogel de silicona; Oxygen transmissibility; Corneal thickness
• ISSN: 1888-4296; 1989-1342
• DOI: 10.1016/j.optom.2014.03.002

Abstract Purpose To compare central corneal swelling after eight hours of sleep in eyes wearing four different silicone hydrogel lenses with three different powers. Methods Twenty-nine neophyte subjects wore lotrafilcon A ( Dk , 140), balafilcon A ( Dk , 91), galyfilcon A ( Dk , 60) and senofilcon A ( Dk , 103) lenses in powers −3.00, −10.00 and +6.00 D on separate nights, in random order, and on one eye only. The contra-lateral eye (no lens) served as the control. Central corneal thickness was measured using a digital optical pachometer before lens insertion and immediately after lens removal on waking. Results For the +6.00 D and −10.00 D, lotrafilcon A induced the least swelling and galyfilcon A the most. The +6.00 D power, averaged across lens materials, induced significantly greater central swelling than the −10.00 and −3.00 D (Re-ANOVA, p < 0.001), (7.7 ± 2.9% vs. 6.8 ± 2.8% and 6.5 ± 2.5% respectively) but there was no difference between −10.00 and −3.00 D. Averaged for power, lotrafilcon A induced the least (6.2 ± 2.8%) and galyfilcon A the most (7.6 ± 3.0%) swelling at the center (Re-ANOVA, p < 0.001). Central corneal swelling with +6.00 D was significantly greater than −10.00 D lens power despite similar levels of average lens transmissibility of these two lens powers. Conclusions The differences in corneal swelling of the lens wearing eyes are consistent with the differences in oxygen transmission of the silicone hydrogel lenses. In silicone hydrogel lenses central corneal swelling is mainly driven by central lens oxygen transmissibility.