Recent Advances in Alcohol-Induced Adduct Formation

• Published in: Alcoholism, clinical and experimental research Vol. 29; no. 7; pp. 1310 - 1316
• Main Authors: Freeman, Thomas L., Tuma, Dean J., Thiele, Geoffrey M., Klassen, Lynell W., Worrall, Simon, Niemelä, Onni, Parkkila, Seppo, Emery, Peter W., Preedy, Victor R.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.07.2005; Lippincott Williams & Wilkins
• Subjects: Acetaldehyde - metabolism; Acetaldehyde - toxicity; Alcohol-Related Disorders - physiopathology; Alcoholism - physiopathology; Alcoholism and acute alcohol poisoning; Animals; Biological and medical sciences; Cardiomyopathy, Alcoholic - physiopathology; DNA Adducts - drug effects; DNA Adducts - physiology; Ethanol - metabolism; Ethanol - toxicity; Humans; Lipid Peroxidation - drug effects; Lipid Peroxidation - physiology; Liver - physiopathology; Liver Diseases, Alcoholic - physiopathology; Malondialdehyde - metabolism; Medical sciences; Muscle, Skeletal - physiopathology; Muscular Diseases - physiopathology; Myocardium - metabolism; Toxicology; Ethanol; Cardiomyopathy; Cardiovascular disease; Lipids; Myocardial disease; Protein Adducts; Protein; Malondialdehyde; Acetaldehyde; Alcoholic beverage; Heart disease; Lipid Peroxidation; Molecular adduct; Adduct; Peroxidation
• ISSN: 0145-6008; 1530-0277
• DOI: 10.1097/01.ALC.0000171484.52201.52

This article presents the proceedings of a symposium presented at the ISBRA 12th World Congress on Biomedical Alcohol Research, held in Heidelberg/Mannheim, Germany, September 29 through October 2, 2004. The organizers of the symposium were Simon Worrall and Victor Preedy, and the symposium was chaired by Onni Niemelä and Geoffrey Thiele. The presentations scheduled for this symposium were (1) Adduct chemistry and mechanisms of adduct formation, by Thomas L. Freeman; (2) Malondialdehyde‐acetaldehyde adducts: the 2004 update, by Geoffrey Thiele; (3) Adduct formation in the liver, by Simon Worrall; (4) Protein adducts in alcoholic cardiomyopathy, by Onni Niemelä; and (5) Alcoholic skeletal muscle myopathy: a role for protein adducts, by Victor R. Preedy.