A long-term serological survey on Aujeszky's disease virus infections in wild boar in East Germany

• Published in: Epidemiology and infection Vol. 140; no. 2; pp. 348 - 358
• Main Authors: PANNWITZ, G., FREULING, C., DENZIN, N., SCHAARSCHMIDT, U., NIEPER, H., HLINAK, A., BURKHARDT, S., KLOPRIES, M., DEDEK, J., HOFFMANN, L., KRAMER, M., SELHORST, T., CONRATHS, F. J., METTENLEITER, T., MÜLLER, T.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.02.2012
• Subjects: Animals; Animals, Wild; Antibodies, Viral - blood; Aujeszky's disease virus; Biological and medical sciences; Disease; Enzyme-Linked Immunosorbent Assay - veterinary; Epidemiology; Female; Fundamental and applied biological sciences. Psychology; Germany - epidemiology; Herpesvirus 1, Suid - immunology; Hogs; Hunting; Immunization; Infections; Laboratories; Male; Microbiology; Miscellaneous; Neutralization Tests - veterinary; Population Surveillance; Pseudorabies; Pseudorabies - epidemiology; Pseudorabies - immunology; Seroepidemiologic Studies; Serology; Serotyping - veterinary; Suid herpesvirus 1; Sus scrofa; Swine; Swine Diseases - epidemiology; Swine Diseases - immunology; Veterinary medicine; Virology; Viruses; Wild boars; East Germany; Europe; Germany; Czech Republic; Sweden; Netherlands; United States > US; Poland; Pomerania; France; Switzerland; Estimating; herpesviruses; prevalence of disease; surveillance; veterinary epidemiology; Herpesviridae; Alphaherpesvirinae; Serology; Epidemiology; Infection; Virus; Aujeszky virus; Vertebrata; Aujeszky disease; Mammalia; Swine; Viral disease; Artiodactyla; Veterinary; Ungulata
• ISSN: 0950-2688; 1469-4409
• DOI: 10.1017/S0950268811000033

Between 1985 and 2008, a total of 102 387 wild boar sera originating from Eastern Germany covering an area of 108 589 km2 were tested for the presence of Aujeszky's disease virus (ADV)-specific antibodies. From 1985 until 1991 and from 1992 until 2008, wild boar sera were exclusively investigated using either conventional seroneutralization assays (n=39 621) or commercial gB and full antigen ELISAs (n=62 766), respectively. Spatial-temporal analysis revealed an increasing ADV seroprevalence from 0·4% to 15·9%, on average, during the 24-year observation period that went along with a continuous spread of the infection in a western direction. During 2006 and 2008, 18% of the 66 affected districts had ADV seroprevalences >30%. There was a significant correlation between ADV seroprevalence and the hunting index of population density (HIPD) of wild boar in the entire study area, although this did not hold true for some regions. Seroprevalences did not differ between sexes but were age-dependent. East Germany has been officially free of Aujeszky's disease (pseudorabies) in domestic pigs since 1985. Although a risk for domestic pigs cannot be completely ruled out, experience has shown that ADV in domestic pigs could be eliminated although the virus was present in the wild boar population. Despite increasing ADV seroprevalence in the East German wild boar population no spillover infections from wild boar to domestic pigs have been reported. To further trace ADV infections in the wild boar population in Germany, a nationwide serological monitoring programme should be implemented.