Role and research progress of hematological markers in laryngeal squamous cell carcinoma

Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only...

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Published inDiagnostic pathology Vol. 18; no. 1; pp. 50 - 16
Main Author Qi, Hui
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 20.04.2023
BioMed Central
BMC
Subjects
Angiogenesis
Apoptosis
Biomarkers
Blood platelets
Cancer
Carcinoma, Squamous Cell - diagnosis
Carcinoma, Squamous Cell - pathology
Care and treatment
Development and progression
Diagnosis
Dysphagia
Head and neck
Head and Neck Neoplasms
Hematological markers
Hematology
Humans
Inflammation
Laryngeal cancer
Laryngeal Neoplasms - diagnosis
Laryngeal Neoplasms - pathology
Laryngeal squamous cell carcinoma
Lymphocytes
Medical prognosis
Metastasis
Neutrophils
Oncology, Experimental
Prognosis
Review
Squamous cell carcinoma
Squamous Cell Carcinoma of Head and Neck
Tumor microenvironment
Tumorigenesis
Tumors
Hematological markers
Inflammation
Prognosis
Tumor microenvironment
Laryngeal squamous cell carcinoma
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Abstract Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC.
AbstractList Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC.
Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC. • The interaction between tumor and inflammation occurs through a variety of complex mechanisms, and inflammation plays an important role in every stage of carcinogenesis, including tumorigenesis, angiogenesis, inhibition of apoptosis, and tumor metastasis. • More than 95% of metastatic malignant tumors have abnormal blood coagulation, and excessive blood coagulation caused by cancer may accelerate the progression and spread of the tumor. • Platelet parameters play an important role in the occurrence and development of malignant tumors. • Cancer-associated nutritional status plays a critical role in the progress of tumors and that these are also closely related to cancer-related cachexia. • There is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma, but the research still has some limitations at present.
Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC. Keywords: Hematological markers, Laryngeal squamous cell carcinoma, Inflammation, Tumor microenvironment, Prognosis
Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC.Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC.
Abstract Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC.
ArticleNumber 50
Audience Academic
Author Qi, Hui
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Issue 1
Keywords Hematological markers
Inflammation
Prognosis
Tumor microenvironment
Laryngeal squamous cell carcinoma
Language English
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Snippet Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and...
Abstract Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the...
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SubjectTerms Angiogenesis
Apoptosis
Biomarkers
Blood platelets
Cancer
Carcinoma, Squamous Cell - diagnosis
Carcinoma, Squamous Cell - pathology
Care and treatment
Development and progression
Diagnosis
Dysphagia
Head and neck
Head and Neck Neoplasms
Hematological markers
Hematology
Humans
Inflammation
Laryngeal cancer
Laryngeal Neoplasms - diagnosis
Laryngeal Neoplasms - pathology
Laryngeal squamous cell carcinoma
Lymphocytes
Medical prognosis
Metastasis
Neutrophils
Oncology, Experimental
Prognosis
Review
Squamous cell carcinoma
Squamous Cell Carcinoma of Head and Neck
Tumor microenvironment
Tumorigenesis
Tumors
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Title Role and research progress of hematological markers in laryngeal squamous cell carcinoma
URI https://www.ncbi.nlm.nih.gov/pubmed/37081512
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Volume 18
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