Role and research progress of hematological markers in laryngeal squamous cell carcinoma

• Published in: Diagnostic pathology Vol. 18; no. 1; pp. 50 - 16
• Main Author: Qi, Hui
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.04.2023; BioMed Central; BMC
• Subjects: Angiogenesis; Apoptosis; Biomarkers; Blood platelets; Cancer; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - pathology; Care and treatment; Development and progression; Diagnosis; Dysphagia; Head and neck; Head and Neck Neoplasms; Hematological markers; Hematology; Humans; Inflammation; Laryngeal cancer; Laryngeal Neoplasms - diagnosis; Laryngeal Neoplasms - pathology; Laryngeal squamous cell carcinoma; Lymphocytes; Medical prognosis; Metastasis; Neutrophils; Oncology, Experimental; Prognosis; Review; Squamous cell carcinoma; Squamous Cell Carcinoma of Head and Neck; Tumor microenvironment; Tumorigenesis; Tumors; Hematological markers; Inflammation; Prognosis; Tumor microenvironment; Laryngeal squamous cell carcinoma
• ISSN: 1746-1596; 1746-1596
• DOI: 10.1186/s13000-023-01335-7

Laryngeal cancer is one of the most common malignant tumors of the head and neck, accounting for about 20%. Due to its high disability rate, the diagnosis and treatment of laryngeal cancer have always been the focus and difficulty of head and neck surgery. The outcome of cancer is affected not only by tumor-related factors but also by host-related factors, especially systemic inflammation, this is usually reflected by a variety of hematological markers. Studies have confirmed that there is a significant correlation between hematological markers and the occurrence, development, and prognosis of laryngeal squamous cell carcinoma (LSCC), and has a certain value in auxiliary diagnosis and prognosis prediction of LSCC. We reviewed various hematological markers related to LSCC aim to summarize the role and research progress of hematological markers in LSCC.