Gonococcal susceptibility to cephalosporins--Hawaii, 2003 to 2011

Among gonococcal isolates examined at the Hawaii State Laboratory Division from 2003 to 2011, the prevalence of elevated cefixime minimum inhibitory concentrations (MICs; ≥0.064 μg/mL) and elevated cefpodoxime MICs (≥0.19 μg/mL) increased over time. In contrast, few isolates exhibited elevated ceftr...

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Published inSexually transmitted diseases Vol. 40; no. 9; p. 756
Main Authors Kidd, Sarah, Lee, Maria V C, Maningas, Eloisa, Komeya, Alan, Kunimoto, Gail, O'Connor, Norman, Katz, Alan R, Wasserman, Glenn M, Kirkcaldy, Robert D, Whelen, A Christian
Format Journal Article
LanguageEnglish
Published United States 01.09.2013
Subjects
Adolescent
Adult
Anti-Bacterial Agents - pharmacology
Cefixime - pharmacology
Cefpodoxime
Ceftizoxime - analogs & derivatives
Ceftizoxime - pharmacology
Ceftriaxone - pharmacology
Drug Resistance, Bacterial
Female
Gonorrhea - drug therapy
Gonorrhea - epidemiology
Gonorrhea - prevention & control
Hawaii - epidemiology
Heterosexuality
Homosexuality, Male
Humans
Male
Microbial Sensitivity Tests
Neisseria gonorrhoeae - drug effects
Neisseria gonorrhoeae - isolation & purification
Population Surveillance
Prevalence
Young Adult
Hawaii
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Summary:Among gonococcal isolates examined at the Hawaii State Laboratory Division from 2003 to 2011, the prevalence of elevated cefixime minimum inhibitory concentrations (MICs; ≥0.064 μg/mL) and elevated cefpodoxime MICs (≥0.19 μg/mL) increased over time. In contrast, few isolates exhibited elevated ceftriaxone MICs (≥0.094 μg/mL), and the prevalence of elevated ceftriaxone MICs did not change.
ISSN:1537-4521
DOI:10.1097/01.olq.0000431357.18959.30