电致化学发光-分子印迹传感器测定L-苯丙氨酸

在三联吡啶钌固相电极上，采用溶胶-凝胶法电沉积分子印迹聚合物，制得电致化学发光-分子印迹传感器。研究了该传感器的电化学和电致化学发光性能。结果表明，此传感器对L-苯丙氨酸具有很高的检测灵敏度和良好的选择性。在优化的条件下，测定L-苯丙氨酸的线性范围为1．0×10^-11～1．0x10^-8mol／L，检出限为3．1x10^-12mol／L。此传感器可应用于尿样中L-苯丙氨酸的测定，回收率为94．8％～110．6％。...

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Bibliographic Details
Published in分析化学 Vol. 41; no. 10; pp. 1543 - 1548
Main Author 丁照云 李春阳 宋启军
Format Journal Article
LanguageChinese
Published 江南大学化学与材料工程学院,无锡,214122 2013
Subjects
L-苯丙氨酸
分子印迹
溶胶-凝胶
电致化学发光
L-Phenylalanine
Molecularly imprinted
Sol-gel
电致化学发光
分子印迹
L-苯丙氨酸
Electrochemiluminescence
溶胶-凝胶
Online AccessGet full text
ISSN0253-3820
DOI10.3724/SP.J.1096.2013.21201

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Summary:在三联吡啶钌固相电极上，采用溶胶-凝胶法电沉积分子印迹聚合物，制得电致化学发光-分子印迹传感器。研究了该传感器的电化学和电致化学发光性能。结果表明，此传感器对L-苯丙氨酸具有很高的检测灵敏度和良好的选择性。在优化的条件下，测定L-苯丙氨酸的线性范围为1．0×10^-11～1．0x10^-8mol／L，检出限为3．1x10^-12mol／L。此传感器可应用于尿样中L-苯丙氨酸的测定，回收率为94．8％～110．6％。
Bibliography:Electrochemiluminescence ; Molecularly imprinted ; L-Phenylalanine ; Sol-gel
DING Zhao-Yun, Li Chun-Yang, SONG Qi-Jun （School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China）
22-1125/O6
A novel ECL-MIP sensor for the determination of L-phenylalanine was reported. The sensor was prepared by the electrodeposition of the molecular imprinting membrance by sol-gel method onto the Ru（bpy）23＋ modified glassy carbon electrode. The electrochemical and eleetrochemiluminescence behavior of the sensor was investigated. The proposed sensor displayed high sensitivity and excellent selectivity for the target molecule L-phenylalanine. Under the optimum conditions, a linear response was observed with the concentrations of L-phenylalanine from 1.0 x 10-11 mol/L to 1.0 x 104 mol/L and the detection limit was 3.1 x 10-12 mol/L. The sensor was successfully applied to the determination of L-phenylalanine in urine samples with the recoveries from 94.8% to 1 10.6%.
ISSN:0253-3820
DOI:10.3724/SP.J.1096.2013.21201